Pain and anxiety are the two main reasons that contribute to the avoidance of dental care. Treating of such patients is stressful for the dentist which might ultimately results in the failure of the treatment as regardless of practioners clinical skills the dental treatment might become compromised without effective pain control system. The ability to provide excellent, high quality pain control in dentistry is required which is based on the practical knowledge of the clinically relevant aspects and updates about the recent advances in the field of local anesthesia. This book gives an exact picture about the recent advances in local anaesthetic agents, delivery methods, its mechanisms which can be highly beneficial in our daily practices.