The fields of medicine and oral medicine are changing and have come a long way. There is still much to be done as far as patient management and accuracy of diagnostic methods is concerned, which will enable the society as a whole to be more productive and healthier. Changes are inevitable, even in the science foundational to the clinical practice of dentistry. Increased diversity and sophistication are developing in the areas of molecular biology, basic science, and social sciences. These will transform our traditional approaches to oral and dental disease management. The recent technological advances in the field of oral medicine that make an impact on clinical dental practice.