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Examination of the effects of neoadjuvant chemoradiotherapy on VEGF expression and on the density of CD8+ tumor infiltrating lymphocytes (TIL) of rectal adenocarcinoma, by comparison of the VEGF expression and the density of CD8+ TIL in endoscopical biopsies before and resection specimens after the therapy, should have an clinical impact in the sense of prognosis of this disease. A trend of inferior prognosis was associated with decrease of VEGF expression. The limitation of our study is the number of patients (53), but it is not excluded that in a larger number of patients predictive or…mehr

Produktbeschreibung
Examination of the effects of neoadjuvant chemoradiotherapy on VEGF expression and on the density of CD8+ tumor infiltrating lymphocytes (TIL) of rectal adenocarcinoma, by comparison of the VEGF expression and the density of CD8+ TIL in endoscopical biopsies before and resection specimens after the therapy, should have an clinical impact in the sense of prognosis of this disease. A trend of inferior prognosis was associated with decrease of VEGF expression. The limitation of our study is the number of patients (53), but it is not excluded that in a larger number of patients predictive or prognostic significance of the density of CD8+ TIL could be detected.
Autorenporträt
My name is David Buka, born in Trutnov in Czech republic in 1982. I have graduated general medicine on Charles University in Prague in 2009, currently working as a radiation oncologist in Teaching hospital in Hradec Kralove, Czech republic.