A kind of drug delivery called a red blood cell membrane disguised nanoparticle drug delivery system involves inserting nanoparticles into the membrane of the red blood cell to be treated, allowing the nanoparticles to circulate throughout the membrane.It is mainly used for the treatment of Photothermal therapy, multidrug resistance, and used as a nanobullets and has anti tumor application. It is a novel type of drug delivery system which is recently arrived since 2-3 years.Graphene oxide many other materials can be used as a carrier in red blood cell membrane camouflaged nanoparticle drug delivery system in the treatment of chemotherapy.