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Significant progress has been made in TB control in the Western Pacific Region in the past decade with a decline in the number of prevalent TB patients and the diagnosis treatment of over 10 million patients. Despite these successes, TB control programs in the Region face significant challenges, such as hard-to-reach vulnerable and marginalized groups in which the TB epidemic tends to concentrate, TB-HIV co-infection and the emergence and spread of drug-resistant TB, especially multi-drug resistant TB (MDR-TB). To mitigate these threats, the Regional Strategy to Stop Tuberculosis in the Western Pacific (2011-2015) was developed in consultation with and endorsed by Member States. The new Strategy builds upon the previous two regional strategic plans and introduces new, evidence-based interventions and technologies in response to the new and emerging challenges.