Regulatory T Cells and Autoimmune Diseases

Herausgeber: Dwivedi, Mitesh Kumar; Fairweather, Delisa

• Broschiertes Buch

Produktbeschreibung

Regulatory T Cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic applications. In particular, this book deals with various Treg-based mechanisms that can lead to autoimmune disease and covers different aspects linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies. This book specifically focuses on Treg-based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood and blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, this book covers vaccine-induced effects on the functioning of Tregs and development of CAR Treg therapy for autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. This book is carefully designed to meet the requirements of both basic and advanced researchers in the area and provide new dimensions and insight into regulatory T cells’ role in autoimmune disease pathogenesis and therapy.

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Produktdetails

• Verlag: Elsevier Science Publishing Co Inc
• Seitenzahl: 982
• Erscheinungstermin: 22. Mai 2024
• Englisch
• Abmessung: 278mm x 215mm
• Gewicht: 2014g
• ISBN-13: 9780443139475
• ISBN-10: 0443139474
• Artikelnr.: 69081008

Inhaltsangabe

Part I Regulatory T cells and immune system 1. Regulatory T cells and their
functions in immune system 2. Regulatory T cells: mechanisms of action 3.
Regulatory T cells and autoimmunity 4. Sex differences in regulatory T
cells during autoimmune disease Part II Role of regulatory T cells in
rheumatic diseases 5. Role of regulatory T cells in pathogenesis and
therapeutics of systemic lupus erythematosus 6. Role of regulatory T cells
in the pathogenesis and therapeutics of primary Sjögren’s syndrome 7. Role
of regulatory T cells in pathogenesis and therapeutics of rheumatoid
arthritis and juvenile idiopathic arthritis 8. Role of regulatory T cells
in pathogenesis and therapeutics of psoriatic arthritis 9. Role of
regulatory T cells in pathogenesis and therapeutics of spondyloarthritis
10. Role of regulatory T cells in pathogenesis and therapeutics of
ankylosing spondylitis Part III Role of regulatory T cells in central
nervous system demyelinating autoimmune diseases 11. Role of regulatory T
cells in pathogenesis and therapeutics of multiple sclerosis 12. Role of
regulatory T cells in the pathogenesis and therapeutics of neuromyelitis
optica spectrum disorder Part IV Role of regulatory T cells in peripheral
nerve, muscle and neuromuscular autoimmune diseases 13. Role of regulatory
T cells in pathogenesis and therapeutics of myasthenia gravis 14. Role of
regulatory T cells in pathogenesis and therapeutics of GuillainBarré
syndrome and experimental autoimmune neuritis 15. Role of regulatory T
cells in pathogenesis and therapeutics of chronic inflammatory
demyelinating polyradiculoneuropathy 16. Role of regulatory T cells in
pathogenesis and therapeutics of dermatomyositis and polymyositis Part V
Role of regulatory T cells in inflammatory bowel diseases 17. Role of
regulatory T cells in pathogenesis and therapeutics of Crohn’s disease and
ulcerative colitis 18. Role of regulatory T cells in pathogenesis and
therapeutics of celiac disease Part VI Role of regulatory T cells in
autoimmune liver diseases 19. Role of regulatory T cells in the
pathogenesis and therapeutics of autoimmune hepatitis 20. Role of
regulatory T cells in pathogenesis and therapeutics of primary biliary
cholangitis and primary sclerosing cholangitis Part VII Role of regulatory
T cells in autoimmune thyroid diseases 21. Role of regulatory T cells in
pathogenesis and therapeutics of Hashimoto’s thyroiditis 22. Role of
regulatory T cells in pathogenesis and therapeutics of Graves’ disease and
Graves’ orbitopathy Part VIII Role of regulatory T cells in autoimmune lung
and kidney diseases 23. Role of regulatory T cells in pathogenesis and
therapeutics of Goodpasture’s syndrome (anti-glomerular basement membrane
disease) 24. Role of regulatory T cells in pathogenesis and therapeutics of
autoimmune glomerulonephritis (IgA vasculitis and IgA nephropathy) Part IX
Role of regulatory T cells in autoimmune skin diseases 25. Role of
regulatory T cells in pathogenesis and therapeutics of vitiligo 26. Role of
regulatory T cells in pathogenesis and therapeutics of psoriasis 27. Role
of regulatory T cells in pathogenesis and therapeutics of atopic dermatitis
28. Role of regulatory T cells in pathogenesis and therapeutics of alopecia
areata 29. Role of regulatory T cells in pathogenesis and therapeutics of
pemphigus vulgaris and bullous pemphigoid 30. Role of regulatory T cells in
pathogenesis and therapeutics of scleroderma (systemic sclerosis) Part X
Role of regulatory T cells in autoimmune blood and blood vessel disorders
31. Role of regulatory T cells in pathogenesis and therapeutics of primary
antiphospholipid syndrome (Hughes syndrome) 32. Role of regulatory T cells
in pathogenesis and therapeutics of Kawasaki disease 33. Role of regulatory
T cells in pathogenesis and therapeutics of Behçet disease 34. Role of
regulatory T cells in pathogenesis and therapeutics of immune
thrombocytopenia 35. Role of regulatory T cells in pathogenesis and
treatment of antineutrophil cytoplasmic antibody-associated vasculitis 36.
Role of regulatory T cells in pathogenesis and therapeutics of autoimmune
hemolytic anemia Part XI Role of regulatory T cells in autoimmune eye
diseases and type 1 diabetes mellitus 37. Role of regulatory T cells in
pathogenesis and therapeutics of autoimmune uveitis 38. Role of regulatory
T cells in pathogenesis and therapeutics of autoimmune retinopathy 39. Role
of regulatory T cell in pathogenesis and therapeutics of type 1 diabetes
mellitus Part XII Current challenges and future prospects in research
towards regulatory T cells based therapeutics in autoimmune diseases 40.
Vaccines induced effects on functioning of regulatory T cells: autoimmune
perspective 41. Probiotic interventions for regulatory T cells’ induction
in autoimmune diseases 42. CAR Treg-based therapeutics for autoimmune
diseases 43. Current challenges and future prospects of regulatory T cells
based therapeutics in autoimmune disease