The Melter War has left the Earth's surface devastated, leaving humanity to survive on what little land is left between the Scorch Zones and the rising oceans, where towering subscrapers dot the dystopian shore lines. Bobbie Chan is a doctor caring for the ultra-elderly in one such subscraper when she notices a mysterious, new disease afflicting her patients; some show signs of age reversal before a catastrophic, and often fatal, cardiac arrest strikes. Bobbie begins to wonder if she is witnessing a bio weapon in full force. A Melter attack? Are they destined to finish the war they started? Belus Corp, the 'savior' of humanity during the Melter War whisk the afflicted away; including Bobbie's grandmother. But Bobbie is terrified. The 'Rejuvenees' are getting younger but they are also becoming increasingly aggressive, uncontrollably so. Bobbie begins a race against time to rescue the Rejuvenees and uncover their true enemy.
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