The study is on relationship of selected blood variables to health related physical fitness of college men (Number OF college student=100, age-18 to 24 years). The variables selected for the study were Hemoglobin, Eosinophil, R.B.C Count, Platelet Count, Clotting Time in case of selected blood variables and the variable For health related physical fitness Grip strength, leg strength, back strength, muscular endurance, Cardio Respiratory Endurance, Body fat percentage, Flexibility. To Find out the relationship of selected blood variables and health related physical fitness. The mean and standard deviation were calculated. To find the relationship person 's product moment correlation were applied at 0.05 level of significance. However, the relationship of hemoglobin with muscular endurance and cardio respiratory endurance and R.B.C Count with cardio respiratory endurance was only Found to be significant at O. 05 level of significance