In this research work, new comprehensive models for prediction of physical properties (viscosity and density) of systems of different alkanolamines were developed. To predict the mass transfer rates and designing and operation of the gas treating units, the accurate determination of the physical properties and modeling of the system plays important role. The physical property of system of aqueous solution of different alkanolamines was modeled using Artificial Neural Network. This has significantly reduced the need for further physicochemical properties measurements for the large number of other potentially interesting alkanolamines blends.