A large number of pathological studies are used to evaluate the patient with renal disease. These are performed alone or in combination for the detection, diagnosis, and/or the evaluation of multiple conditions. They are principally required to assess urinary tract obstruction, kidney stones, renal cyst or mass, disorders with characteristic histopathological findings, renal vascular diseases. Because of safety, ease of use, and the information provided, the most commonly used pathological technique in patients presenting with renal disease is renal histhopathology.