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The pathogenesis of visceral leishmaniasis (VL) is associated with altered chemokine expression and impaired migration of inflammatory cells. Apoptosis is associated with resolution of inflammation. However, in kidneys of dogs infected with Leishmania infantum, apoptosis seems to act as a marker of inflammatory activity rather than as a resolution event, in contrast to inflammatory recruitment. This book addresses aspects related to characterizing and quantifying some molecules related to apoptosis, and inflammation; and correlating these findings with clinical symptomatology and with the…mehr

Produktbeschreibung
The pathogenesis of visceral leishmaniasis (VL) is associated with altered chemokine expression and impaired migration of inflammatory cells. Apoptosis is associated with resolution of inflammation. However, in kidneys of dogs infected with Leishmania infantum, apoptosis seems to act as a marker of inflammatory activity rather than as a resolution event, in contrast to inflammatory recruitment. This book addresses aspects related to characterizing and quantifying some molecules related to apoptosis, and inflammation; and correlating these findings with clinical symptomatology and with the renal histopathological lesions caused by L. infantum in naturally infected dogs.
Autorenporträt
Bárbara Laurice Araújo Verçosa graduated in Veterinary Medicine from the Federal University of Piauí (2007), Master in General Pathology and PhD in Sciences from the Federal University of Minas Gerais (2010). She completed a post doctorate in Immunology at the University of Brasília (2010).