Malaria endemic countries are faced with a challenge of drug resistance to anti-malarial drugs. The switch to new malaria treatments using ACTs is costly.The rationale for this book is to analyze data aiming to answer the question regarding the effectiveness of three malaria treatments by using endpoints that consider healthcare utilization and access to care looking at the parents' initiative to seek medical care of their children otherthan the scheduled active follow ups in controlled clinical trials. Understanding patients' perception of their health in relation to anti-malarial drug regimens is important given the burden of costs of these drugs. It impact on the adherence to treatment and the motivation of patients to seek care which may led to drug resistance even with the newly developed drug. This books is useful to public health specialists, policy makers, statisticians and researchers in the health sector with an interest of coming up with sustainable malaria treatments,effective planning of policy changes and appropriate analysis of trials with multiple events