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High Quality Content by WIKIPEDIA articles! A repeated measures design is a longitudinal study, usually a controlled experiment but sometimes an observational study (often referred to as a longitudinal or panel study). A popular repeated-measures design is the crossover study. A crossover study is a longitudinal study in which subjects receive a sequence of different treatments (or exposures). While crossover studies can be observational studies, many important crossover studies are controlled experiments, which are discussed in this article. Crossover designs are common for experiments in many scientific disciplines, for example psychology, education, pharmaceutical science, and health-care, especially medicine.