Replicative Fitness of Human Immunodeficiency Viruses - Ariën, Kevin
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Pioneering studies on HIV fitness have shown that fitness is related to disease progression and may have important clinical relevance, both in untreated and treated HIV-positive subjects. In this doctoral thesis, we have used a wide variety of predominantly primary patient HIV isolates, originating from diverse regions in the world to further explore the impact of HIV replicative fitness on the infected individual, but also on the temporal evolution of the HIV epidemic.

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Produktbeschreibung
Pioneering studies on HIV fitness have shown that fitness is related to disease progression and may have important clinical relevance, both in untreated and treated HIV-positive subjects. In this doctoral thesis, we have used a wide variety of predominantly primary patient HIV isolates, originating from diverse regions in the world to further explore the impact of HIV replicative fitness on the infected individual, but also on the temporal evolution of the HIV epidemic.
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Autorenporträt
Dr. Ariën obtained his PhD in 2005 from the University of Antwerp and did a postdoc at Ghent University looking at the impact of the accessory protein Nef on HIV replication and interactions with cellular cofactors. Currently, Kevin works as a group leader at the Institute of Tropical Medicine, Antwerp on HIV fitness, transmission and microbicides.