Reproductive Toxicology

Herausgeber: Kapp, Robert W.; Tyl, Rochelle W.

• Gebundenes Buch

Produktbeschreibung

Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded Third Edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicologya (TM)s contributors are experienced regulatory agency and Clinical Research Organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research. This ground-breaking resource includes: * New and important critical mechanistic topics such as epigenetics and omics * The first significant compilation of epigenetic mechanisms * An in-depth analysis of the role of genomics, proteomics, and metabolomicsin human reproduction * New guidelines with respect to the latest research applications in the field

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Produktdetails

• Verlag: CRC Press
• 3. Auflage
• Seitenzahl: 424
• Erscheinungstermin: 20. September 2010
• Englisch
• Abmessung: 240mm x 161mm x 27mm
• Gewicht: 798g
• ISBN-13: 9781420073430
• ISBN-10: 1420073435
• Artikelnr.: 23141095

Autorenporträt

Robert W. Kapp, Rochelle W. Tyl

Inhaltsangabe

Section I: Normal Reproduction and Development. 1. Biology and Physiology
of Fertilization. 2. Normal Development of the Male Reproduction System. 3.
Normal Development of the Female Reproduction System. 4. Development of the
Mammalian Nervous System. Section II: Regulatory Evaluation of
Reproduction. 5. EPA and OECD Perspectives on Reproductive and
Developmental Toxicity Testing. 6. FDA and ICH Perspectives on Reproductive
and Developmental Toxicity Testing. 7. Reproductive Study Evolution and IND
Submissions. Section III: Developmental Toxicity of Systemic Organ Systems.
8. Developmental Immunotoxicity. 9. Developmental Neurotoxicity. 10.
Developmental Toxicology of the Respiratory System. 11. Developmental
Toxicology of the Renal System. 12. Developmental Toxicology of the Liver.
13. Cardiovascular Development and Malformation. Section IV: Toxicity of
the Reproductive Process. 14. Male Reproductive Toxicity. 15. Female
Reproductive Toxicity. 16. Toxicity of Pregnant Female Reproductive System.
17. Epigenetic Reproductive Toxicants. 18. Endocrine Disruption Effects on
Reproductive Development and Adult Reproduction. 19. Metals and Metal
Compounds in Reproductive and Developmental Toxicology. 20. -omics in
Reproductive and Developmental Toxicology.