Karen B. Schmaling, Robert M. Kaplan

Rethinking Clinical Research

Methodology and Ethics

• Broschiertes Buch

Produktbeschreibung

Challenging traditional methodologies, this analysis uncovers biases in health research. Covering fundamental principles, tools, and ethics, it offers in-depth case examples. Aimed at students and professionals, it promotes critical evaluation for a nuanced understanding of evidence production.

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Produktdetails

• Verlag: Cambridge University Press
• Seitenzahl: 250
• Erscheinungstermin: 28. Februar 2025
• Englisch
• ISBN-13: 9781009391726
• ISBN-10: 1009391720
• Artikelnr.: 72110065

Autorenporträt

Karen B. Schmaling is a professor of clinical psychology at Washington State University. She has over 150 publications that have been cited over 12,000 times. Her research has been supported by the US National Institutes of Health and National Science Foundation.

Inhaltsangabe

Introduction
Part I. Fundamentals: 1. 'Can it work? Does it work? Is it worth it?'
2. Core research tools
3. Clinical research ethics
Part II. Rethinking research: 4. Asking the right questions
5. Bias in randomized controlled trials
6. Is bigger always better?: On sample size, statistical significance, and big data
7. Achieving transparency
8. Understanding and restraining study costs
9. Implementation: getting the right interventions to market
10. Health outcomes: a comprehensive approach
11. Confronting the crises in peer review and academic publishing
12. Ontologies: promoting a shared scientific mission
Part III. Case studies: 13. Case study: treating gastroesophageal disease with Omeprazole
14. Case study: statin therapy for primary prevention of heart disease
15. Case study: cancer screening
16. Case study: antidepressant medications
17. Conclusions and recommendations.