Review: Synthetic methods and anti-microbial importance of thiazole - Thorat, Bapu;Thorat, Vaishali;Joshi, Vinay
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Data on the synthesis of thiazoles systems from thioamide, thiourea, thiosemicarbazide, and labile sulfur was reviewed. The principal directions in the practical application of these substances are briefly discussed. Thiazole derivatives are important class of sulfur containing heterocyclic compounds, found in many potent biologically active molecules such as Cefdinir (antibacterial drug, semisynthetic third generation cephalosporin drug), flucloxacillin (androgenic steroid danazol), Pramipexole (The dopamine D2-agonist), Sulfathiazol (antimicrobial drug), Ritonavir (The HIV-1 protease…mehr

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Produktbeschreibung
Data on the synthesis of thiazoles systems from thioamide, thiourea, thiosemicarbazide, and labile sulfur was reviewed. The principal directions in the practical application of these substances are briefly discussed. Thiazole derivatives are important class of sulfur containing heterocyclic compounds, found in many potent biologically active molecules such as Cefdinir (antibacterial drug, semisynthetic third generation cephalosporin drug), flucloxacillin (androgenic steroid danazol), Pramipexole (The dopamine D2-agonist), Sulfathiazol (antimicrobial drug), Ritonavir (The HIV-1 protease inhibitor, antiretroviral drug), Famotidine (H2-receptor antagonist), Febuxostat (Xanthine oxidase inhibitor), Ziprasidone (Antipsychotic agent), etc. Thiazole derivatives were scanned against different bacteria and fungi, some of the derivatives shows strong anti-microbial activity was summarized.
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Autorenporträt
Dr. Bapu R Thorat ¿ Ph.D. in chemistry published more than 88 research papers, and 18 books, has 2 patents in his credits.Dr. Rupali Manikrao Biradar - Ph.D. in Botany has 15 years of research experience. Expert in chromatography and applied science.Megha Rai has published 72 research papers and completed one major research project at UGC.