The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system.
The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system.
Section 1: INTRODUCTION TO THE AREA. 1.Therapeutic Promise of the Eicosanoid Area: An Overview. Section 2: INHIBITORS OF EICOSANOID PRODUCTION. 1.Antiphospholipase Proteins: Introduction and Overview. 2. Effects of Corticosteroids on Release of Eicosanoid Precursors. 3. Drugs that Inhibit the Activities or Activation of Phospholipases and Other Acylhydrolases. 4. Cyclooxygenase Inhibitors. 5. Lipoxygenase Inhibitors. 6. Selective Inhibitors of Thromboxane Synthetase. Section 3: MODULATORS OF EICOSANOID ACTIONS. 1. Classification of Prostanoid Receptors. 2. Eicosanoid Receptor Antagonists.3. Leukotriene Antagonists. 4.Regulation of Cyclic Nucleotide Metabolism in Human Platelets by Prostanoids. 5. Opposite Effects of Prostaglandins on Human Platelets Mediated by Distinct Protein Kinases. Index.
Section 1: INTRODUCTION TO THE AREA. 1.Therapeutic Promise of the Eicosanoid Area: An Overview. Section 2: INHIBITORS OF EICOSANOID PRODUCTION. 1.Antiphospholipase Proteins: Introduction and Overview. 2. Effects of Corticosteroids on Release of Eicosanoid Precursors. 3. Drugs that Inhibit the Activities or Activation of Phospholipases and Other Acylhydrolases. 4. Cyclooxygenase Inhibitors. 5. Lipoxygenase Inhibitors. 6. Selective Inhibitors of Thromboxane Synthetase. Section 3: MODULATORS OF EICOSANOID ACTIONS. 1. Classification of Prostanoid Receptors. 2. Eicosanoid Receptor Antagonists.3. Leukotriene Antagonists. 4.Regulation of Cyclic Nucleotide Metabolism in Human Platelets by Prostanoids. 5. Opposite Effects of Prostaglandins on Human Platelets Mediated by Distinct Protein Kinases. Index.
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