Rheumatoid Arthritis: A Clinical Handbook
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Rheumatoid Arthritis: A Clinical Handbook

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Rheumatic arthritis (RA) is the condition in which the body's immune system attacks the joints. This causes the tissue lining of the synovium to thicken, leading to swelling and pain around the joints. If the inflammation is not controlled, it can damage the bone and cartilage. Over time, joints become loose, painful and unstable, and lose their mobility. RA most commonly affects women between the ages of 30 and 60, while in men it occurs later in life. The development of RA is subject to an interplay between genetic and environmental factors. Close to a hundred different genes have been impli...