JOSE A. OTEO / KARIM E. HECHEMYFrom Genome to Proteome, Pathobiology, and Rickettsiae as an International Threat, Volume 1063
Rickettsioses
From Genome to Proteome, Pathobiology, and Rickettsiae as an International Threat, Volume 1063
Herausgeber: Oteo, Jose A; Blanco, José R; Silverman, David J; Raoult, Didier A; Hechemy, Karim E
JOSE A. OTEO / KARIM E. HECHEMYFrom Genome to Proteome, Pathobiology, and Rickettsiae as an International Threat, Volume 1063
Rickettsioses
From Genome to Proteome, Pathobiology, and Rickettsiae as an International Threat, Volume 1063
Herausgeber: Oteo, Jose A; Blanco, José R; Silverman, David J; Raoult, Didier A; Hechemy, Karim E
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Rickettsial diseases have affected humanity since the dawn of civilization. Despite the advent of effective antibiotic therapy, humans continue to be afflicted by rickettsial diseases, which still often go undiagnosed because of their protean clinical manifestations. During the past decade, several major developments have occurred in rickettsiology. With the advent of the newly emerging infections caused by a number of rickettsias, the re-emerging of old pathogenic species of rickettsias that cause both old and new syndromes has helped redefine the level of rickettsial pathogenicity. The…mehr
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Rickettsial diseases have affected humanity since the dawn of civilization. Despite the advent of effective antibiotic therapy, humans continue to be afflicted by rickettsial diseases, which still often go undiagnosed because of their protean clinical manifestations. During the past decade, several major developments have occurred in rickettsiology. With the advent of the newly emerging infections caused by a number of rickettsias, the re-emerging of old pathogenic species of rickettsias that cause both old and new syndromes has helped redefine the level of rickettsial pathogenicity. The intracellular nature of most rickettsias remains a mystery although their genome size is close to that of the free-living neisserias. Advances in molecular techniques have also helped redefine and reclassify rickettsias by maintaining some in the order Rickettsiales and placing others in other bacterial orders. The latter are still included in rickettsial reviews because of historical precedence. These molecular advances also help us to refine our knowledge of rickettsial pathogenesis. This volume is the first of two volumes to result from the 4th International Conference on Rickettsiae and Rickettsial Diseases, in which an effort is made to address and clarify issues from clinical, diagnostic, epidemiologic, and molecular perspectives that have remained unsolved in the past. In this volume, several subdisciplines of rickettsiology are included: genomics and proteomics, a protocol for naming newly isolated rickettsiae; bioterrorism; the pathobiology of reckettsial infections including Q (query) fever, antibiotic resistance, and vaccines; the discovery of new ricketsiae; and the pathobiology of Ehrlichia and Anaplasma infections. This volume. along with Century of Rickettsiology, which will be published in 2006 as an Annals volume, will provide a complete picture of the world-wide range of work that is currently being carried out in the field of rickettsiology. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.
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Produktdetails
- Produktdetails
- Verlag: Wiley
- Seitenzahl: 496
- Erscheinungstermin: 1. August 2006
- Englisch
- Abmessung: 229mm x 152mm x 27mm
- Gewicht: 711g
- ISBN-13: 9781573316019
- ISBN-10: 1573316016
- Artikelnr.: 23822023
- Herstellerkennzeichnung
- Libri GmbH
- Europaallee 1
- 36244 Bad Hersfeld
- gpsr@libri.de
- Verlag: Wiley
- Seitenzahl: 496
- Erscheinungstermin: 1. August 2006
- Englisch
- Abmessung: 229mm x 152mm x 27mm
- Gewicht: 711g
- ISBN-13: 9781573316019
- ISBN-10: 1573316016
- Artikelnr.: 23822023
- Herstellerkennzeichnung
- Libri GmbH
- Europaallee 1
- 36244 Bad Hersfeld
- gpsr@libri.de
Jose A. Oteo is the editor of Rickettsioses: From Genome to Proteome, Pathobiology, and Rickettsiae as an International Threat, Volume 1063, published by Wiley. Karim E. Hechemy is the editor of Rickettsioses: From Genome to Proteome, Pathobiology, and Rickettsiae as an International Threat, Volume 1063, published by Wiley.
Introduction:. New Insights into Rickettsioses: Genomics
Proteomics
Pathobiology
and the International Threat of Rickettsial Diseases: Introduction: Karim E. Hechemy
José A. Oteo
Didier Raoult
David J. Silverman
and José Ramón Blanco. Naming of Rickettsiae and Rickettsial Diseases: Didier Raoult
Pierre-Edouard Fournier
Marina Eremeeva
Stephen Graves
Patrick J. Kelly
José A. Oteo
Zuzana Sekeyova
Akira Tamura
Irina Tarasevich
And Lijuan Zhang. . Part I: Genomics and Proteomics:. 1. Progress in Rickettsial Genome Analysis from Pioneering of Rickettsia prowazekii to the Recent Rickettsia typhi: David H. Walker and Xue-Jie Yu. 2. Rickettsia felis
from Culture to Genome Sequencing: H Ogata
C Robert
S Audic
S Robineau
G Blanc
P E Fournier
P Renesto
J M Claverie
and D Raoult. 3. Dissecting the Rickettsia prowazekii Genome: Genetic and Proteomic Approaches: Aimee M. Tucker
Lewis K. Pannell
and David O. Wood. 4. New Perspectives on Rickettsial Evolution from New Genome Sequences of Rickettsia
particularly R. canadensis
and Orientia tsutsugamushi: Marina E. Eremeeva
Anup Madan
Chris D. Shaw
Kevin Tang
and Gregory A. Dasch. 5. Preliminary Assessment of Genome Differences between the Reference Nine Mile Isolate and Two Human Endocarditis Isolates of Coxiella burnetii: Paul A. Beare
Stephen F. Porcella
Rekha Seshadri
James E. Samuel
and Robert A. Heinzen. 6. Fur-Regulated Genes in Coxiella burnetii: Heather L. Briggs
Mary J. Wilson
Rekha Seshadri
and James E. Samuel. 7. A Minimal Set of DNA Repair Genes Is Sufficient for Survival of Coxiella burnetii under Oxidative Stress: K Mertens
L Lantsheer
and J E Samuel. 8. Identification
Cloning
and Expression of Potential Diagnostic Markers for Q Fever: C C Chao
H W Chen
X Li
W B Xu
B Hanson
and W M Ching. 9. Preliminary Transcriptional Analysis of spoT Gene Family and of Membrane Proteins in Rickettsia conorii and Rickettsia felis: C Rovery
M V La
S Robineau
K Matsumoto
P Renesto
and D Raoult. 10. Phylogenic Analysis of Rickettsial Patatin-like Protein with Conserved Phospholipase A2 Active Sites: Guillaume Blanc
Patricia Renesto
and Didier Raoult. 11. Proteomic Analysis of Rickettsia prowazekii: C C Chao
D Chelius
T Zhang
E Mutumanje
and W M Ching. 12. Rickettsia conorii and R. prowazekii Proteome Analysis by 2DE-MS: A Step toward Functional Analysis of Rickettsial Genomes: Patricia Renesto
Saïd Azza
Alain Dolla
Patrick Fourquet
Guy Vestris
Jean-Pierre Gorvel
and Didier Raoult. 13. Phylogenetic Study of Rickettsia Species Using Sequences of the Autotransporter Protein-Encoding Gene sca2: Maxime Ngwamidiba
Guillaume Blanc
Hiroyuki Ogata
Didier Raoult
and Pierre-Edouard Fournier. 14. Molecular Characterization of a Group of Proteins Containing Ankyrin Repeats in Orientia tsutsugamushi: Nam-Hyuk Cho
Jo-Min Kim
Eun-Kyung Kwon
Se-Yoon Kim
Seung-Hoon Han
Hyuk Chu
Jung-Hee Lee
Myung-Sik Choi
and Ik-Sang Kim. 15. Ehrlichia ruminantium: A Promiscuous Genome: Maria Allsopp
Helena Steyn
Erich Zweygarth
and Basil Allsopp. Part II: Pathobiology of Q Fever Infection:. 16. Coxiella burnetii Infection: Jan Kazar. 17. Coxiella burnetii Whole Cell Lysate Protein Identification by Mass Spectrometry and Tandem Mass Spectrometry: Ludovit Skultety
Lenka Hernychova
Rudolf Toman
Martin Hubalek
Katarina Slaba
Jana Zechovska
Veronika Stofanikova
Juraj Lenco
Jiri Stulik
and Ales Macela. 18. Replication of Coxiella burnetii Is Inhibited in CHO K-1 Cells Treated with Inhibitors of Cholesterol Metabolism: Dale Howe and Robert A. Heinzen. 19. Protective Immunity against Q Fever Induced with a Recombinant P1 Antigen Fused with HspB of Coxiella burnetii: Qingfeng Li
Dongsheng Niu
Bohai Wen
Meiling Chen
Ling Qiu
and Jingbo Zhang. 20. Immunization Experiments with Recombinant Coxiella burnetii Proteins in a Murine Infection Model: Judith Tyczka
Sandra Eberling
and Georg Baljer. 21. Structural and Functional Characterization of the Glycan Antigens Involved in Immunobiology of Q Fever: Pavol Vadovic
Katarina Slaba
Marcela Fodorova
Ludovit Skultety
and Rudolf Toman. 22. Lack of Dendritic Cell Maturation Following Infection by Coxiella burnetii Synthesizing Different Lipopolysaccharide Chemotypes: Jeffrey G. Shannon
Dale Howe
and Robert A. Heinzen. 23. TLR2 Is Necessary to Inflammatory Response in Coxiella burnetii Infection: Soraya Meghari
Amélie Honstettre
Hubert Lepidi
Bernardt Ryffel
Didier Raoult
and Jean-Louis Mege. 24. Comparative Virulence of Phase I and II Coxiella burnetii in Immunodeficient Mice: Masako Andoh
Kasi E. Russell-Lodrigue
Guoquan Zhang
and James E. Samuel. 25. Balb/c Mouse Model and Real-Time Quantitative Polymerase Chain Reaction for Evaluation of the Immunoprotectivity against Q Fever: Jingbo Zhang
Bohai Wen
Meiling Chen
Jun Zhang
and Dongsheng Niu. 26. Hepatitis Associated with C. burnetii Isolates: K E Russell-Lodrigue
M W J Poels
G Q Zhang
D N Mcmurray
and J E Samuel. 27. Q Fever Research Group (QRG)
Adelaide: Activities-Exit Summary 1980-2004: B Marmion
R Harris
P Storm
K Helbig
I Penttila
D Worswick
and L Semendric. Part III: Pathobiology of Rickettsial Infection
Antibiotic Resistance
and Vaccines:. 28. Rickettsial Infections: Juan P. Olano. 29. The Presence of Eschars
but Not Greater Severity
in Portuguese Patients Infected with Israeli Spotted Fever: Rita De Sousa
Nahed Ismail
Sónia Dória-Nóbrega
Pedro Costa
Tiago Abreu
Ana França
Mário Amaro
Paula Proença
Paula Brito
José Poças
Teresa Ramos
Graça Cristina
Graça Pombo
Liliana Vitorino
Jorge Torgal
Fátima Bacellar
and David Walker. 30. Similarities and Differences in Host Cell Signaling following Infection with Different Rickettsia Species: Elena Rydkina
David J. Silverman
and Sanjeev K. Sahni. 31. Potential Roles for Regulatory Oxygenases in Rickettsial Pathogenesis: Sanjeev K. Sahni
Elena Rydkina
Abha Sahni
Suresh G. Joshi
and David J. Silverman. 32. Growth of Typhus Group and Spotted Fever Group Rickettsiae in Insect Cells: Tsuneo Uchiyama. 33. Genome Comparison Analysis of Molecular Mechanisms of Resistance to Antibiotics in the Rickettsia Genus: J M Rolain And D Raoult. 34. Cloning and Sequence Analysis of the 22-kDa Antigen Genes of Orientia tsutsugamushi Strains Kato
TA763
AFSC 7
18-032460
TH1814
and MAK 119: Hong Ge
Min Tong
Andrew Li
Rajan Mehta
and Wei-Mei Ching. 35. Nitric Oxide as a Mediator of Increased Microvascular Permeability during Acute Rickettsioses: Michael E. Woods
Gary Wen
and Juan P. Olano. 36. Cloning and Expression of 51-kDa Antigenic Protein of Neorickettsia risticii NR-JA1: Myeong-Kyu Park
Eun-Ha Kim
Mae-Rim Cho
Ying-Hua Yi
Mi-Jin Lee
Devendra H. Shah
Jin-Ho Park
Bae-Keun Park
Seong-Kug Eo
John-Hwa Lee
and Joon-Seok Chae. 37. Activity of Telithromycin against Thirteen New Isolates of C. burnetii Including Three Resistant to Doxycycline: Jean-Marc Rolain
Frédéric Lambert
and Didier Raoult. 38. Effect of Antibiotic Treatment in Patients with DEBONEL/TIBOLA: V Ibarra
J R Blanco
A Portillo
S Santibáñez
L Metola
and J A Oteo. 39. Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus: Marcela Fodorova
Pavol Vadovic
Ludovit Skultety
Katarina Slaba
and Rudolf Toman. 40. Analysis of Immunoprotectivity of the Recombinant OmpA of Rickettsia heilongjiangensis: Yanmei Jiao
Bohai Wen
Meiling Chen
Dongsheng Niu
Jun Zhang
and Ling Qiu. 41. Short- and Long-Term Immune Responses of CD-1 Outbred Mice to the Scrub Typhus DNA Vaccine Candidate: p47Kp: Guang Xu
Suchismita Chattopadhyay
Ju Jiang
Teik-Chye Chan
Chien-Chung Chao
Wei-Mei Ching
and Allen L. Richards. Part IV: Bartonella:. 42. Bartonellae as Elegant Hemotropic Parasites: Richard J. Birtles. 43. Production of Recombinant Protein Pap31 and Its Application for the Diagnosis of Bartonella bacilliformis Infection: A Taye
H Chen
K Duncan
Z Zhang
L Hendrix
J Gonzalez
and W Ching. 44. Bartonella bacilliformis GroEL: Effect on Growth of Human Vascular Endothelial Cells in Infected Cocultures: Laura S. Smitherman and Michael F. Minnick. 45. Occurrence of Bartonella henselae and Bartonella quintana among Human Immunodeficiency Virus-Infected Patients: M Pape
P Kollaras
K Mandraveli
A Tsona
S Metallidis
P Nikolaidis
and S Alexiou-Daniel. 46. Bacillary Angiomatosis Caused by Bartonella Quintana: Montserrat Sala
Bernat Font
Isabel Sanfeliu
Mariela Quesada
Imma Ponts
and Ferran Segura. 47. Molecular Screening of Bartonella Species in Rodents from the Russian Far East: Oleg Mediannikov
Leonid Ivanov
Nina Zdanovskaya
Nelya Vysochina
Pierre-Edouard Fournier
Irina Tarasevich
and Didier Raoult. 48. Characterization of Genes Involved in Long-Term Bacteremia in Mice by Bartonella birtlesii: Maria Mavris
Henri Saenz
Martine Monteil
Henri-Jean Boulouis
Christoph Dehio
and Muriel Vayssier-Taussat. Part V: New Rickettsiae or Rickettsiae Not Previously or Recently Known to Cause Human Infection:. 49. Rickettsia parkeri as a Paradigm for Multiple Causes of Tick-Borne Spotted Fever in the Western Hemisphere: Christopher D. Paddock. 50. Detection of a Typhus Group Rickettsia in Amblyomma Ticks in the State of Nuevo Leon
Mexico: Aaron Medina-Sanchez
Donald H. Bouyer
Virginia Alcantara-Rodriguez
Claudio Mafra
Jorge Zavala-Castro
Ted Whitworth
Vsevolod L. Popov
Ildefonso Fernandez-Salas
and David H. Walker. 51. Detection of a Non-Pathogenic Variant of Anaplasma phagocytophilum in Ixodes ricinus from La Rioja
Spain: A Portillo
A S Santos
S Santibáñez
L Pérez-Martínez
J R Blanco
V Ibarra
and J A Oteo. 52. Phylogenetic Analysis of a Novel Molecular Isolate of Spotted Fever Group Rickettsiae from Northern Peru: Candidatus Rickettsia andeanae: Ju Jiang
Patrick J. Blair
Vidal Felices
Cecilia Moron
Manuel Cespedes
Elizabeth Anaya
George B. Schoeler
John W. Sumner
James G. Olson
and Allen L. Richards. 53. Molecular and Biological Characterization of a Novel Coxiella-like Agent from Carios capensis: Will K. Reeves
Amanda D. Loftis
Rachael A. Priestley
William Wills
Felicia Sanders
And Gregory A. Dasch. 54. DEBONEL/TIBOLA: Is Rickettsia slovaca the Only Etiological Agent?: V Ibarra
A Portillo
S Santibáñez
J R Blanco
L Pérez-Martínez
J Márquez
And J A Oteo. 55. Low Risk of Developing Human Rickettsia aeschlimannii Infection in the North of Spain: J A Oteo
A Portillo
J R Blanco
V Ibarra
L Pérez-Martínez
C Izco
A Pérez-Palacios
and S Jiménez. 56. Novel Spotted Fever Group Rickettsiae (SFGR) Infecting Amblyomma americanum Ticks in Ohio
USA: D J Kelly
J R Carmichael
G C Booton
K F Poetter
And P A Fuerst. 57. Old and New Human Rickettsiosis in Minas Gerais State
Brazil: S B Calic
C M Barcellos-Rocha
R C Leite
C L Mafra
and M A M Galvão. 58. Ehrlichia ruminantium: An Emerging Human Pathogen?: M T E P Allsopp
M Louw
And E C Meyer. Part VI: Pathobiology of Ehrlichia and Anaplasma Infections:. 59. Anaplasma and Ehrlichia Infection: J Stephen Dumler. 60. The Interactions of Anaplasma phagocytophilum
Endothelial Cells
and Human Neutrophils: Michael J. Herron
Marna E. Ericson
Timothy J. Kurtti
and Ulrike G. Munderloh. 61. Balancing Protective Immunity and Immunopathology: A Unifying Model of Monocytotropic Ehrlichiosis: Nahed Ismail and David H. Walker. 62. Susceptibility and Resistance to Monocytic Ehrlichiosis in the Mouse: Gary M. Winslow
Constantine Bitsaktsis
and Eric Yager. 63. Overcoming Barriers to the Transformation of the Genus Ehrlichia: S Wesley Long
Ted J. Whitworth
David H. Walker
and Xue-Jie Yu. 64. Mechanisms of Immunological Control of Anaplasma phagocytophilum in Mice: Christina Rinkler
Yvonne Kern
Christian Bogdan
and Friederike D. Von Loewenich. 65. Platelet Dysfunction after Association with Anaplasma phagocytophilum in Vitro: Dori L. Borjesson
Jennifer L. Brazzell
and Regina Feferman. 66. Anaplasma phagocytophilum Infection Reduces Expression of Phagocytosis-Related Receptors on Neutrophils: Justin W. A. Garyu and J Stephen Dumler. 67. Analysis of Ehrlichial p28 Gene Expression in a Murine Model of Persistent Infection: Patricia A. Crocquet-Valdes
Jere W. Mcbride
Hui-Min Feng
Nahed Ismail
Melissa A. Small
Xue-Jie Yu
and David H. Walker. 68. Innate Immune Tissue Injury and Murine HGA: Tissue Injury in the Murine Model of Granulocytic Anaplasmosis Relates to Host Innate Immune Response and Not Pathogen Load: Diana G. Scorpio
Friederike D. Von Loewenich
Christian Bogdan
and J Stephen Dumler. 69. Cytokine Responses in Dogs Infected with Ehrlichia canis Oklahoma Strain: Tomoko Tajima and Yasuko Rikihisa. 70. Molecular Characterization of E. canis gp36 and E. chaffeensis gp47 Tandem Repeats among Isolates from Different Geographic Locations: C Kuyler Doyle
Ana Maria Cardenas
Daniel M. Aguiar
Marcelo B. Labruna
Lucy M. Ndip
Xue-Jie Yu
and Jere W. Mcbride. 71. Prophylactic Use of Sustained-Release Doxycycline Blocks Tick-Transmitted Infection by Anaplasma phagocytophilum in a Murine Model: Robert F. Massung
Nordin S. Zeidner
Marc C. Dolan
Dawn Roellig
Elizabeth Gabitzsch
Danielle R. Troughton
and Michael L. Levin. 72. Concentration of Procalcitonin and C-Reactive Protein in Patients with Human Granulocytic Anaplasmosis and the Initial Phase of Tick-Borne Encephalitis: Stanka Lotric-Furlan
Tereza Rojko
and Franc Strle. Part VII: Ricketsiae Agents of Bioterrorism:. 73. Genome Analysis of Coxiella burnetii Species: Insights into Pathogenesis and Evolution and Implications for Biodefense: Rekha Seshadri and James Samuel. 74. Attack Scenarios with Rickettsial Species: Implications for Response and Management: G Pappas
N Akritidis
and E V Tsianos. 75. The Pathogen Resource Integration Center: Implications for Rickettsial Research: Mark E. Hance
Michael J. Czar
Abdu Azad
Anjan Purkayastha
Eric E. Snyder
Oswald R. Crasta
Joao C. Setubal
and Bruno W. Sobral. 76. Evaluation of Low Concentration Aerosol for Infecting Humans with the Q Fever Pathogen: Eugene Vorobeychikov
Alexander Vasilenko
Nikolay Tokarevich
Ludmila Yakovleva
and Boris Nikolaev. Index of Contributors
Proteomics
Pathobiology
and the International Threat of Rickettsial Diseases: Introduction: Karim E. Hechemy
José A. Oteo
Didier Raoult
David J. Silverman
and José Ramón Blanco. Naming of Rickettsiae and Rickettsial Diseases: Didier Raoult
Pierre-Edouard Fournier
Marina Eremeeva
Stephen Graves
Patrick J. Kelly
José A. Oteo
Zuzana Sekeyova
Akira Tamura
Irina Tarasevich
And Lijuan Zhang. . Part I: Genomics and Proteomics:. 1. Progress in Rickettsial Genome Analysis from Pioneering of Rickettsia prowazekii to the Recent Rickettsia typhi: David H. Walker and Xue-Jie Yu. 2. Rickettsia felis
from Culture to Genome Sequencing: H Ogata
C Robert
S Audic
S Robineau
G Blanc
P E Fournier
P Renesto
J M Claverie
and D Raoult. 3. Dissecting the Rickettsia prowazekii Genome: Genetic and Proteomic Approaches: Aimee M. Tucker
Lewis K. Pannell
and David O. Wood. 4. New Perspectives on Rickettsial Evolution from New Genome Sequences of Rickettsia
particularly R. canadensis
and Orientia tsutsugamushi: Marina E. Eremeeva
Anup Madan
Chris D. Shaw
Kevin Tang
and Gregory A. Dasch. 5. Preliminary Assessment of Genome Differences between the Reference Nine Mile Isolate and Two Human Endocarditis Isolates of Coxiella burnetii: Paul A. Beare
Stephen F. Porcella
Rekha Seshadri
James E. Samuel
and Robert A. Heinzen. 6. Fur-Regulated Genes in Coxiella burnetii: Heather L. Briggs
Mary J. Wilson
Rekha Seshadri
and James E. Samuel. 7. A Minimal Set of DNA Repair Genes Is Sufficient for Survival of Coxiella burnetii under Oxidative Stress: K Mertens
L Lantsheer
and J E Samuel. 8. Identification
Cloning
and Expression of Potential Diagnostic Markers for Q Fever: C C Chao
H W Chen
X Li
W B Xu
B Hanson
and W M Ching. 9. Preliminary Transcriptional Analysis of spoT Gene Family and of Membrane Proteins in Rickettsia conorii and Rickettsia felis: C Rovery
M V La
S Robineau
K Matsumoto
P Renesto
and D Raoult. 10. Phylogenic Analysis of Rickettsial Patatin-like Protein with Conserved Phospholipase A2 Active Sites: Guillaume Blanc
Patricia Renesto
and Didier Raoult. 11. Proteomic Analysis of Rickettsia prowazekii: C C Chao
D Chelius
T Zhang
E Mutumanje
and W M Ching. 12. Rickettsia conorii and R. prowazekii Proteome Analysis by 2DE-MS: A Step toward Functional Analysis of Rickettsial Genomes: Patricia Renesto
Saïd Azza
Alain Dolla
Patrick Fourquet
Guy Vestris
Jean-Pierre Gorvel
and Didier Raoult. 13. Phylogenetic Study of Rickettsia Species Using Sequences of the Autotransporter Protein-Encoding Gene sca2: Maxime Ngwamidiba
Guillaume Blanc
Hiroyuki Ogata
Didier Raoult
and Pierre-Edouard Fournier. 14. Molecular Characterization of a Group of Proteins Containing Ankyrin Repeats in Orientia tsutsugamushi: Nam-Hyuk Cho
Jo-Min Kim
Eun-Kyung Kwon
Se-Yoon Kim
Seung-Hoon Han
Hyuk Chu
Jung-Hee Lee
Myung-Sik Choi
and Ik-Sang Kim. 15. Ehrlichia ruminantium: A Promiscuous Genome: Maria Allsopp
Helena Steyn
Erich Zweygarth
and Basil Allsopp. Part II: Pathobiology of Q Fever Infection:. 16. Coxiella burnetii Infection: Jan Kazar. 17. Coxiella burnetii Whole Cell Lysate Protein Identification by Mass Spectrometry and Tandem Mass Spectrometry: Ludovit Skultety
Lenka Hernychova
Rudolf Toman
Martin Hubalek
Katarina Slaba
Jana Zechovska
Veronika Stofanikova
Juraj Lenco
Jiri Stulik
and Ales Macela. 18. Replication of Coxiella burnetii Is Inhibited in CHO K-1 Cells Treated with Inhibitors of Cholesterol Metabolism: Dale Howe and Robert A. Heinzen. 19. Protective Immunity against Q Fever Induced with a Recombinant P1 Antigen Fused with HspB of Coxiella burnetii: Qingfeng Li
Dongsheng Niu
Bohai Wen
Meiling Chen
Ling Qiu
and Jingbo Zhang. 20. Immunization Experiments with Recombinant Coxiella burnetii Proteins in a Murine Infection Model: Judith Tyczka
Sandra Eberling
and Georg Baljer. 21. Structural and Functional Characterization of the Glycan Antigens Involved in Immunobiology of Q Fever: Pavol Vadovic
Katarina Slaba
Marcela Fodorova
Ludovit Skultety
and Rudolf Toman. 22. Lack of Dendritic Cell Maturation Following Infection by Coxiella burnetii Synthesizing Different Lipopolysaccharide Chemotypes: Jeffrey G. Shannon
Dale Howe
and Robert A. Heinzen. 23. TLR2 Is Necessary to Inflammatory Response in Coxiella burnetii Infection: Soraya Meghari
Amélie Honstettre
Hubert Lepidi
Bernardt Ryffel
Didier Raoult
and Jean-Louis Mege. 24. Comparative Virulence of Phase I and II Coxiella burnetii in Immunodeficient Mice: Masako Andoh
Kasi E. Russell-Lodrigue
Guoquan Zhang
and James E. Samuel. 25. Balb/c Mouse Model and Real-Time Quantitative Polymerase Chain Reaction for Evaluation of the Immunoprotectivity against Q Fever: Jingbo Zhang
Bohai Wen
Meiling Chen
Jun Zhang
and Dongsheng Niu. 26. Hepatitis Associated with C. burnetii Isolates: K E Russell-Lodrigue
M W J Poels
G Q Zhang
D N Mcmurray
and J E Samuel. 27. Q Fever Research Group (QRG)
Adelaide: Activities-Exit Summary 1980-2004: B Marmion
R Harris
P Storm
K Helbig
I Penttila
D Worswick
and L Semendric. Part III: Pathobiology of Rickettsial Infection
Antibiotic Resistance
and Vaccines:. 28. Rickettsial Infections: Juan P. Olano. 29. The Presence of Eschars
but Not Greater Severity
in Portuguese Patients Infected with Israeli Spotted Fever: Rita De Sousa
Nahed Ismail
Sónia Dória-Nóbrega
Pedro Costa
Tiago Abreu
Ana França
Mário Amaro
Paula Proença
Paula Brito
José Poças
Teresa Ramos
Graça Cristina
Graça Pombo
Liliana Vitorino
Jorge Torgal
Fátima Bacellar
and David Walker. 30. Similarities and Differences in Host Cell Signaling following Infection with Different Rickettsia Species: Elena Rydkina
David J. Silverman
and Sanjeev K. Sahni. 31. Potential Roles for Regulatory Oxygenases in Rickettsial Pathogenesis: Sanjeev K. Sahni
Elena Rydkina
Abha Sahni
Suresh G. Joshi
and David J. Silverman. 32. Growth of Typhus Group and Spotted Fever Group Rickettsiae in Insect Cells: Tsuneo Uchiyama. 33. Genome Comparison Analysis of Molecular Mechanisms of Resistance to Antibiotics in the Rickettsia Genus: J M Rolain And D Raoult. 34. Cloning and Sequence Analysis of the 22-kDa Antigen Genes of Orientia tsutsugamushi Strains Kato
TA763
AFSC 7
18-032460
TH1814
and MAK 119: Hong Ge
Min Tong
Andrew Li
Rajan Mehta
and Wei-Mei Ching. 35. Nitric Oxide as a Mediator of Increased Microvascular Permeability during Acute Rickettsioses: Michael E. Woods
Gary Wen
and Juan P. Olano. 36. Cloning and Expression of 51-kDa Antigenic Protein of Neorickettsia risticii NR-JA1: Myeong-Kyu Park
Eun-Ha Kim
Mae-Rim Cho
Ying-Hua Yi
Mi-Jin Lee
Devendra H. Shah
Jin-Ho Park
Bae-Keun Park
Seong-Kug Eo
John-Hwa Lee
and Joon-Seok Chae. 37. Activity of Telithromycin against Thirteen New Isolates of C. burnetii Including Three Resistant to Doxycycline: Jean-Marc Rolain
Frédéric Lambert
and Didier Raoult. 38. Effect of Antibiotic Treatment in Patients with DEBONEL/TIBOLA: V Ibarra
J R Blanco
A Portillo
S Santibáñez
L Metola
and J A Oteo. 39. Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus: Marcela Fodorova
Pavol Vadovic
Ludovit Skultety
Katarina Slaba
and Rudolf Toman. 40. Analysis of Immunoprotectivity of the Recombinant OmpA of Rickettsia heilongjiangensis: Yanmei Jiao
Bohai Wen
Meiling Chen
Dongsheng Niu
Jun Zhang
and Ling Qiu. 41. Short- and Long-Term Immune Responses of CD-1 Outbred Mice to the Scrub Typhus DNA Vaccine Candidate: p47Kp: Guang Xu
Suchismita Chattopadhyay
Ju Jiang
Teik-Chye Chan
Chien-Chung Chao
Wei-Mei Ching
and Allen L. Richards. Part IV: Bartonella:. 42. Bartonellae as Elegant Hemotropic Parasites: Richard J. Birtles. 43. Production of Recombinant Protein Pap31 and Its Application for the Diagnosis of Bartonella bacilliformis Infection: A Taye
H Chen
K Duncan
Z Zhang
L Hendrix
J Gonzalez
and W Ching. 44. Bartonella bacilliformis GroEL: Effect on Growth of Human Vascular Endothelial Cells in Infected Cocultures: Laura S. Smitherman and Michael F. Minnick. 45. Occurrence of Bartonella henselae and Bartonella quintana among Human Immunodeficiency Virus-Infected Patients: M Pape
P Kollaras
K Mandraveli
A Tsona
S Metallidis
P Nikolaidis
and S Alexiou-Daniel. 46. Bacillary Angiomatosis Caused by Bartonella Quintana: Montserrat Sala
Bernat Font
Isabel Sanfeliu
Mariela Quesada
Imma Ponts
and Ferran Segura. 47. Molecular Screening of Bartonella Species in Rodents from the Russian Far East: Oleg Mediannikov
Leonid Ivanov
Nina Zdanovskaya
Nelya Vysochina
Pierre-Edouard Fournier
Irina Tarasevich
and Didier Raoult. 48. Characterization of Genes Involved in Long-Term Bacteremia in Mice by Bartonella birtlesii: Maria Mavris
Henri Saenz
Martine Monteil
Henri-Jean Boulouis
Christoph Dehio
and Muriel Vayssier-Taussat. Part V: New Rickettsiae or Rickettsiae Not Previously or Recently Known to Cause Human Infection:. 49. Rickettsia parkeri as a Paradigm for Multiple Causes of Tick-Borne Spotted Fever in the Western Hemisphere: Christopher D. Paddock. 50. Detection of a Typhus Group Rickettsia in Amblyomma Ticks in the State of Nuevo Leon
Mexico: Aaron Medina-Sanchez
Donald H. Bouyer
Virginia Alcantara-Rodriguez
Claudio Mafra
Jorge Zavala-Castro
Ted Whitworth
Vsevolod L. Popov
Ildefonso Fernandez-Salas
and David H. Walker. 51. Detection of a Non-Pathogenic Variant of Anaplasma phagocytophilum in Ixodes ricinus from La Rioja
Spain: A Portillo
A S Santos
S Santibáñez
L Pérez-Martínez
J R Blanco
V Ibarra
and J A Oteo. 52. Phylogenetic Analysis of a Novel Molecular Isolate of Spotted Fever Group Rickettsiae from Northern Peru: Candidatus Rickettsia andeanae: Ju Jiang
Patrick J. Blair
Vidal Felices
Cecilia Moron
Manuel Cespedes
Elizabeth Anaya
George B. Schoeler
John W. Sumner
James G. Olson
and Allen L. Richards. 53. Molecular and Biological Characterization of a Novel Coxiella-like Agent from Carios capensis: Will K. Reeves
Amanda D. Loftis
Rachael A. Priestley
William Wills
Felicia Sanders
And Gregory A. Dasch. 54. DEBONEL/TIBOLA: Is Rickettsia slovaca the Only Etiological Agent?: V Ibarra
A Portillo
S Santibáñez
J R Blanco
L Pérez-Martínez
J Márquez
And J A Oteo. 55. Low Risk of Developing Human Rickettsia aeschlimannii Infection in the North of Spain: J A Oteo
A Portillo
J R Blanco
V Ibarra
L Pérez-Martínez
C Izco
A Pérez-Palacios
and S Jiménez. 56. Novel Spotted Fever Group Rickettsiae (SFGR) Infecting Amblyomma americanum Ticks in Ohio
USA: D J Kelly
J R Carmichael
G C Booton
K F Poetter
And P A Fuerst. 57. Old and New Human Rickettsiosis in Minas Gerais State
Brazil: S B Calic
C M Barcellos-Rocha
R C Leite
C L Mafra
and M A M Galvão. 58. Ehrlichia ruminantium: An Emerging Human Pathogen?: M T E P Allsopp
M Louw
And E C Meyer. Part VI: Pathobiology of Ehrlichia and Anaplasma Infections:. 59. Anaplasma and Ehrlichia Infection: J Stephen Dumler. 60. The Interactions of Anaplasma phagocytophilum
Endothelial Cells
and Human Neutrophils: Michael J. Herron
Marna E. Ericson
Timothy J. Kurtti
and Ulrike G. Munderloh. 61. Balancing Protective Immunity and Immunopathology: A Unifying Model of Monocytotropic Ehrlichiosis: Nahed Ismail and David H. Walker. 62. Susceptibility and Resistance to Monocytic Ehrlichiosis in the Mouse: Gary M. Winslow
Constantine Bitsaktsis
and Eric Yager. 63. Overcoming Barriers to the Transformation of the Genus Ehrlichia: S Wesley Long
Ted J. Whitworth
David H. Walker
and Xue-Jie Yu. 64. Mechanisms of Immunological Control of Anaplasma phagocytophilum in Mice: Christina Rinkler
Yvonne Kern
Christian Bogdan
and Friederike D. Von Loewenich. 65. Platelet Dysfunction after Association with Anaplasma phagocytophilum in Vitro: Dori L. Borjesson
Jennifer L. Brazzell
and Regina Feferman. 66. Anaplasma phagocytophilum Infection Reduces Expression of Phagocytosis-Related Receptors on Neutrophils: Justin W. A. Garyu and J Stephen Dumler. 67. Analysis of Ehrlichial p28 Gene Expression in a Murine Model of Persistent Infection: Patricia A. Crocquet-Valdes
Jere W. Mcbride
Hui-Min Feng
Nahed Ismail
Melissa A. Small
Xue-Jie Yu
and David H. Walker. 68. Innate Immune Tissue Injury and Murine HGA: Tissue Injury in the Murine Model of Granulocytic Anaplasmosis Relates to Host Innate Immune Response and Not Pathogen Load: Diana G. Scorpio
Friederike D. Von Loewenich
Christian Bogdan
and J Stephen Dumler. 69. Cytokine Responses in Dogs Infected with Ehrlichia canis Oklahoma Strain: Tomoko Tajima and Yasuko Rikihisa. 70. Molecular Characterization of E. canis gp36 and E. chaffeensis gp47 Tandem Repeats among Isolates from Different Geographic Locations: C Kuyler Doyle
Ana Maria Cardenas
Daniel M. Aguiar
Marcelo B. Labruna
Lucy M. Ndip
Xue-Jie Yu
and Jere W. Mcbride. 71. Prophylactic Use of Sustained-Release Doxycycline Blocks Tick-Transmitted Infection by Anaplasma phagocytophilum in a Murine Model: Robert F. Massung
Nordin S. Zeidner
Marc C. Dolan
Dawn Roellig
Elizabeth Gabitzsch
Danielle R. Troughton
and Michael L. Levin. 72. Concentration of Procalcitonin and C-Reactive Protein in Patients with Human Granulocytic Anaplasmosis and the Initial Phase of Tick-Borne Encephalitis: Stanka Lotric-Furlan
Tereza Rojko
and Franc Strle. Part VII: Ricketsiae Agents of Bioterrorism:. 73. Genome Analysis of Coxiella burnetii Species: Insights into Pathogenesis and Evolution and Implications for Biodefense: Rekha Seshadri and James Samuel. 74. Attack Scenarios with Rickettsial Species: Implications for Response and Management: G Pappas
N Akritidis
and E V Tsianos. 75. The Pathogen Resource Integration Center: Implications for Rickettsial Research: Mark E. Hance
Michael J. Czar
Abdu Azad
Anjan Purkayastha
Eric E. Snyder
Oswald R. Crasta
Joao C. Setubal
and Bruno W. Sobral. 76. Evaluation of Low Concentration Aerosol for Infecting Humans with the Q Fever Pathogen: Eugene Vorobeychikov
Alexander Vasilenko
Nikolay Tokarevich
Ludmila Yakovleva
and Boris Nikolaev. Index of Contributors
Introduction:. New Insights into Rickettsioses: Genomics
Proteomics
Pathobiology
and the International Threat of Rickettsial Diseases: Introduction: Karim E. Hechemy
José A. Oteo
Didier Raoult
David J. Silverman
and José Ramón Blanco. Naming of Rickettsiae and Rickettsial Diseases: Didier Raoult
Pierre-Edouard Fournier
Marina Eremeeva
Stephen Graves
Patrick J. Kelly
José A. Oteo
Zuzana Sekeyova
Akira Tamura
Irina Tarasevich
And Lijuan Zhang. . Part I: Genomics and Proteomics:. 1. Progress in Rickettsial Genome Analysis from Pioneering of Rickettsia prowazekii to the Recent Rickettsia typhi: David H. Walker and Xue-Jie Yu. 2. Rickettsia felis
from Culture to Genome Sequencing: H Ogata
C Robert
S Audic
S Robineau
G Blanc
P E Fournier
P Renesto
J M Claverie
and D Raoult. 3. Dissecting the Rickettsia prowazekii Genome: Genetic and Proteomic Approaches: Aimee M. Tucker
Lewis K. Pannell
and David O. Wood. 4. New Perspectives on Rickettsial Evolution from New Genome Sequences of Rickettsia
particularly R. canadensis
and Orientia tsutsugamushi: Marina E. Eremeeva
Anup Madan
Chris D. Shaw
Kevin Tang
and Gregory A. Dasch. 5. Preliminary Assessment of Genome Differences between the Reference Nine Mile Isolate and Two Human Endocarditis Isolates of Coxiella burnetii: Paul A. Beare
Stephen F. Porcella
Rekha Seshadri
James E. Samuel
and Robert A. Heinzen. 6. Fur-Regulated Genes in Coxiella burnetii: Heather L. Briggs
Mary J. Wilson
Rekha Seshadri
and James E. Samuel. 7. A Minimal Set of DNA Repair Genes Is Sufficient for Survival of Coxiella burnetii under Oxidative Stress: K Mertens
L Lantsheer
and J E Samuel. 8. Identification
Cloning
and Expression of Potential Diagnostic Markers for Q Fever: C C Chao
H W Chen
X Li
W B Xu
B Hanson
and W M Ching. 9. Preliminary Transcriptional Analysis of spoT Gene Family and of Membrane Proteins in Rickettsia conorii and Rickettsia felis: C Rovery
M V La
S Robineau
K Matsumoto
P Renesto
and D Raoult. 10. Phylogenic Analysis of Rickettsial Patatin-like Protein with Conserved Phospholipase A2 Active Sites: Guillaume Blanc
Patricia Renesto
and Didier Raoult. 11. Proteomic Analysis of Rickettsia prowazekii: C C Chao
D Chelius
T Zhang
E Mutumanje
and W M Ching. 12. Rickettsia conorii and R. prowazekii Proteome Analysis by 2DE-MS: A Step toward Functional Analysis of Rickettsial Genomes: Patricia Renesto
Saïd Azza
Alain Dolla
Patrick Fourquet
Guy Vestris
Jean-Pierre Gorvel
and Didier Raoult. 13. Phylogenetic Study of Rickettsia Species Using Sequences of the Autotransporter Protein-Encoding Gene sca2: Maxime Ngwamidiba
Guillaume Blanc
Hiroyuki Ogata
Didier Raoult
and Pierre-Edouard Fournier. 14. Molecular Characterization of a Group of Proteins Containing Ankyrin Repeats in Orientia tsutsugamushi: Nam-Hyuk Cho
Jo-Min Kim
Eun-Kyung Kwon
Se-Yoon Kim
Seung-Hoon Han
Hyuk Chu
Jung-Hee Lee
Myung-Sik Choi
and Ik-Sang Kim. 15. Ehrlichia ruminantium: A Promiscuous Genome: Maria Allsopp
Helena Steyn
Erich Zweygarth
and Basil Allsopp. Part II: Pathobiology of Q Fever Infection:. 16. Coxiella burnetii Infection: Jan Kazar. 17. Coxiella burnetii Whole Cell Lysate Protein Identification by Mass Spectrometry and Tandem Mass Spectrometry: Ludovit Skultety
Lenka Hernychova
Rudolf Toman
Martin Hubalek
Katarina Slaba
Jana Zechovska
Veronika Stofanikova
Juraj Lenco
Jiri Stulik
and Ales Macela. 18. Replication of Coxiella burnetii Is Inhibited in CHO K-1 Cells Treated with Inhibitors of Cholesterol Metabolism: Dale Howe and Robert A. Heinzen. 19. Protective Immunity against Q Fever Induced with a Recombinant P1 Antigen Fused with HspB of Coxiella burnetii: Qingfeng Li
Dongsheng Niu
Bohai Wen
Meiling Chen
Ling Qiu
and Jingbo Zhang. 20. Immunization Experiments with Recombinant Coxiella burnetii Proteins in a Murine Infection Model: Judith Tyczka
Sandra Eberling
and Georg Baljer. 21. Structural and Functional Characterization of the Glycan Antigens Involved in Immunobiology of Q Fever: Pavol Vadovic
Katarina Slaba
Marcela Fodorova
Ludovit Skultety
and Rudolf Toman. 22. Lack of Dendritic Cell Maturation Following Infection by Coxiella burnetii Synthesizing Different Lipopolysaccharide Chemotypes: Jeffrey G. Shannon
Dale Howe
and Robert A. Heinzen. 23. TLR2 Is Necessary to Inflammatory Response in Coxiella burnetii Infection: Soraya Meghari
Amélie Honstettre
Hubert Lepidi
Bernardt Ryffel
Didier Raoult
and Jean-Louis Mege. 24. Comparative Virulence of Phase I and II Coxiella burnetii in Immunodeficient Mice: Masako Andoh
Kasi E. Russell-Lodrigue
Guoquan Zhang
and James E. Samuel. 25. Balb/c Mouse Model and Real-Time Quantitative Polymerase Chain Reaction for Evaluation of the Immunoprotectivity against Q Fever: Jingbo Zhang
Bohai Wen
Meiling Chen
Jun Zhang
and Dongsheng Niu. 26. Hepatitis Associated with C. burnetii Isolates: K E Russell-Lodrigue
M W J Poels
G Q Zhang
D N Mcmurray
and J E Samuel. 27. Q Fever Research Group (QRG)
Adelaide: Activities-Exit Summary 1980-2004: B Marmion
R Harris
P Storm
K Helbig
I Penttila
D Worswick
and L Semendric. Part III: Pathobiology of Rickettsial Infection
Antibiotic Resistance
and Vaccines:. 28. Rickettsial Infections: Juan P. Olano. 29. The Presence of Eschars
but Not Greater Severity
in Portuguese Patients Infected with Israeli Spotted Fever: Rita De Sousa
Nahed Ismail
Sónia Dória-Nóbrega
Pedro Costa
Tiago Abreu
Ana França
Mário Amaro
Paula Proença
Paula Brito
José Poças
Teresa Ramos
Graça Cristina
Graça Pombo
Liliana Vitorino
Jorge Torgal
Fátima Bacellar
and David Walker. 30. Similarities and Differences in Host Cell Signaling following Infection with Different Rickettsia Species: Elena Rydkina
David J. Silverman
and Sanjeev K. Sahni. 31. Potential Roles for Regulatory Oxygenases in Rickettsial Pathogenesis: Sanjeev K. Sahni
Elena Rydkina
Abha Sahni
Suresh G. Joshi
and David J. Silverman. 32. Growth of Typhus Group and Spotted Fever Group Rickettsiae in Insect Cells: Tsuneo Uchiyama. 33. Genome Comparison Analysis of Molecular Mechanisms of Resistance to Antibiotics in the Rickettsia Genus: J M Rolain And D Raoult. 34. Cloning and Sequence Analysis of the 22-kDa Antigen Genes of Orientia tsutsugamushi Strains Kato
TA763
AFSC 7
18-032460
TH1814
and MAK 119: Hong Ge
Min Tong
Andrew Li
Rajan Mehta
and Wei-Mei Ching. 35. Nitric Oxide as a Mediator of Increased Microvascular Permeability during Acute Rickettsioses: Michael E. Woods
Gary Wen
and Juan P. Olano. 36. Cloning and Expression of 51-kDa Antigenic Protein of Neorickettsia risticii NR-JA1: Myeong-Kyu Park
Eun-Ha Kim
Mae-Rim Cho
Ying-Hua Yi
Mi-Jin Lee
Devendra H. Shah
Jin-Ho Park
Bae-Keun Park
Seong-Kug Eo
John-Hwa Lee
and Joon-Seok Chae. 37. Activity of Telithromycin against Thirteen New Isolates of C. burnetii Including Three Resistant to Doxycycline: Jean-Marc Rolain
Frédéric Lambert
and Didier Raoult. 38. Effect of Antibiotic Treatment in Patients with DEBONEL/TIBOLA: V Ibarra
J R Blanco
A Portillo
S Santibáñez
L Metola
and J A Oteo. 39. Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus: Marcela Fodorova
Pavol Vadovic
Ludovit Skultety
Katarina Slaba
and Rudolf Toman. 40. Analysis of Immunoprotectivity of the Recombinant OmpA of Rickettsia heilongjiangensis: Yanmei Jiao
Bohai Wen
Meiling Chen
Dongsheng Niu
Jun Zhang
and Ling Qiu. 41. Short- and Long-Term Immune Responses of CD-1 Outbred Mice to the Scrub Typhus DNA Vaccine Candidate: p47Kp: Guang Xu
Suchismita Chattopadhyay
Ju Jiang
Teik-Chye Chan
Chien-Chung Chao
Wei-Mei Ching
and Allen L. Richards. Part IV: Bartonella:. 42. Bartonellae as Elegant Hemotropic Parasites: Richard J. Birtles. 43. Production of Recombinant Protein Pap31 and Its Application for the Diagnosis of Bartonella bacilliformis Infection: A Taye
H Chen
K Duncan
Z Zhang
L Hendrix
J Gonzalez
and W Ching. 44. Bartonella bacilliformis GroEL: Effect on Growth of Human Vascular Endothelial Cells in Infected Cocultures: Laura S. Smitherman and Michael F. Minnick. 45. Occurrence of Bartonella henselae and Bartonella quintana among Human Immunodeficiency Virus-Infected Patients: M Pape
P Kollaras
K Mandraveli
A Tsona
S Metallidis
P Nikolaidis
and S Alexiou-Daniel. 46. Bacillary Angiomatosis Caused by Bartonella Quintana: Montserrat Sala
Bernat Font
Isabel Sanfeliu
Mariela Quesada
Imma Ponts
and Ferran Segura. 47. Molecular Screening of Bartonella Species in Rodents from the Russian Far East: Oleg Mediannikov
Leonid Ivanov
Nina Zdanovskaya
Nelya Vysochina
Pierre-Edouard Fournier
Irina Tarasevich
and Didier Raoult. 48. Characterization of Genes Involved in Long-Term Bacteremia in Mice by Bartonella birtlesii: Maria Mavris
Henri Saenz
Martine Monteil
Henri-Jean Boulouis
Christoph Dehio
and Muriel Vayssier-Taussat. Part V: New Rickettsiae or Rickettsiae Not Previously or Recently Known to Cause Human Infection:. 49. Rickettsia parkeri as a Paradigm for Multiple Causes of Tick-Borne Spotted Fever in the Western Hemisphere: Christopher D. Paddock. 50. Detection of a Typhus Group Rickettsia in Amblyomma Ticks in the State of Nuevo Leon
Mexico: Aaron Medina-Sanchez
Donald H. Bouyer
Virginia Alcantara-Rodriguez
Claudio Mafra
Jorge Zavala-Castro
Ted Whitworth
Vsevolod L. Popov
Ildefonso Fernandez-Salas
and David H. Walker. 51. Detection of a Non-Pathogenic Variant of Anaplasma phagocytophilum in Ixodes ricinus from La Rioja
Spain: A Portillo
A S Santos
S Santibáñez
L Pérez-Martínez
J R Blanco
V Ibarra
and J A Oteo. 52. Phylogenetic Analysis of a Novel Molecular Isolate of Spotted Fever Group Rickettsiae from Northern Peru: Candidatus Rickettsia andeanae: Ju Jiang
Patrick J. Blair
Vidal Felices
Cecilia Moron
Manuel Cespedes
Elizabeth Anaya
George B. Schoeler
John W. Sumner
James G. Olson
and Allen L. Richards. 53. Molecular and Biological Characterization of a Novel Coxiella-like Agent from Carios capensis: Will K. Reeves
Amanda D. Loftis
Rachael A. Priestley
William Wills
Felicia Sanders
And Gregory A. Dasch. 54. DEBONEL/TIBOLA: Is Rickettsia slovaca the Only Etiological Agent?: V Ibarra
A Portillo
S Santibáñez
J R Blanco
L Pérez-Martínez
J Márquez
And J A Oteo. 55. Low Risk of Developing Human Rickettsia aeschlimannii Infection in the North of Spain: J A Oteo
A Portillo
J R Blanco
V Ibarra
L Pérez-Martínez
C Izco
A Pérez-Palacios
and S Jiménez. 56. Novel Spotted Fever Group Rickettsiae (SFGR) Infecting Amblyomma americanum Ticks in Ohio
USA: D J Kelly
J R Carmichael
G C Booton
K F Poetter
And P A Fuerst. 57. Old and New Human Rickettsiosis in Minas Gerais State
Brazil: S B Calic
C M Barcellos-Rocha
R C Leite
C L Mafra
and M A M Galvão. 58. Ehrlichia ruminantium: An Emerging Human Pathogen?: M T E P Allsopp
M Louw
And E C Meyer. Part VI: Pathobiology of Ehrlichia and Anaplasma Infections:. 59. Anaplasma and Ehrlichia Infection: J Stephen Dumler. 60. The Interactions of Anaplasma phagocytophilum
Endothelial Cells
and Human Neutrophils: Michael J. Herron
Marna E. Ericson
Timothy J. Kurtti
and Ulrike G. Munderloh. 61. Balancing Protective Immunity and Immunopathology: A Unifying Model of Monocytotropic Ehrlichiosis: Nahed Ismail and David H. Walker. 62. Susceptibility and Resistance to Monocytic Ehrlichiosis in the Mouse: Gary M. Winslow
Constantine Bitsaktsis
and Eric Yager. 63. Overcoming Barriers to the Transformation of the Genus Ehrlichia: S Wesley Long
Ted J. Whitworth
David H. Walker
and Xue-Jie Yu. 64. Mechanisms of Immunological Control of Anaplasma phagocytophilum in Mice: Christina Rinkler
Yvonne Kern
Christian Bogdan
and Friederike D. Von Loewenich. 65. Platelet Dysfunction after Association with Anaplasma phagocytophilum in Vitro: Dori L. Borjesson
Jennifer L. Brazzell
and Regina Feferman. 66. Anaplasma phagocytophilum Infection Reduces Expression of Phagocytosis-Related Receptors on Neutrophils: Justin W. A. Garyu and J Stephen Dumler. 67. Analysis of Ehrlichial p28 Gene Expression in a Murine Model of Persistent Infection: Patricia A. Crocquet-Valdes
Jere W. Mcbride
Hui-Min Feng
Nahed Ismail
Melissa A. Small
Xue-Jie Yu
and David H. Walker. 68. Innate Immune Tissue Injury and Murine HGA: Tissue Injury in the Murine Model of Granulocytic Anaplasmosis Relates to Host Innate Immune Response and Not Pathogen Load: Diana G. Scorpio
Friederike D. Von Loewenich
Christian Bogdan
and J Stephen Dumler. 69. Cytokine Responses in Dogs Infected with Ehrlichia canis Oklahoma Strain: Tomoko Tajima and Yasuko Rikihisa. 70. Molecular Characterization of E. canis gp36 and E. chaffeensis gp47 Tandem Repeats among Isolates from Different Geographic Locations: C Kuyler Doyle
Ana Maria Cardenas
Daniel M. Aguiar
Marcelo B. Labruna
Lucy M. Ndip
Xue-Jie Yu
and Jere W. Mcbride. 71. Prophylactic Use of Sustained-Release Doxycycline Blocks Tick-Transmitted Infection by Anaplasma phagocytophilum in a Murine Model: Robert F. Massung
Nordin S. Zeidner
Marc C. Dolan
Dawn Roellig
Elizabeth Gabitzsch
Danielle R. Troughton
and Michael L. Levin. 72. Concentration of Procalcitonin and C-Reactive Protein in Patients with Human Granulocytic Anaplasmosis and the Initial Phase of Tick-Borne Encephalitis: Stanka Lotric-Furlan
Tereza Rojko
and Franc Strle. Part VII: Ricketsiae Agents of Bioterrorism:. 73. Genome Analysis of Coxiella burnetii Species: Insights into Pathogenesis and Evolution and Implications for Biodefense: Rekha Seshadri and James Samuel. 74. Attack Scenarios with Rickettsial Species: Implications for Response and Management: G Pappas
N Akritidis
and E V Tsianos. 75. The Pathogen Resource Integration Center: Implications for Rickettsial Research: Mark E. Hance
Michael J. Czar
Abdu Azad
Anjan Purkayastha
Eric E. Snyder
Oswald R. Crasta
Joao C. Setubal
and Bruno W. Sobral. 76. Evaluation of Low Concentration Aerosol for Infecting Humans with the Q Fever Pathogen: Eugene Vorobeychikov
Alexander Vasilenko
Nikolay Tokarevich
Ludmila Yakovleva
and Boris Nikolaev. Index of Contributors
Proteomics
Pathobiology
and the International Threat of Rickettsial Diseases: Introduction: Karim E. Hechemy
José A. Oteo
Didier Raoult
David J. Silverman
and José Ramón Blanco. Naming of Rickettsiae and Rickettsial Diseases: Didier Raoult
Pierre-Edouard Fournier
Marina Eremeeva
Stephen Graves
Patrick J. Kelly
José A. Oteo
Zuzana Sekeyova
Akira Tamura
Irina Tarasevich
And Lijuan Zhang. . Part I: Genomics and Proteomics:. 1. Progress in Rickettsial Genome Analysis from Pioneering of Rickettsia prowazekii to the Recent Rickettsia typhi: David H. Walker and Xue-Jie Yu. 2. Rickettsia felis
from Culture to Genome Sequencing: H Ogata
C Robert
S Audic
S Robineau
G Blanc
P E Fournier
P Renesto
J M Claverie
and D Raoult. 3. Dissecting the Rickettsia prowazekii Genome: Genetic and Proteomic Approaches: Aimee M. Tucker
Lewis K. Pannell
and David O. Wood. 4. New Perspectives on Rickettsial Evolution from New Genome Sequences of Rickettsia
particularly R. canadensis
and Orientia tsutsugamushi: Marina E. Eremeeva
Anup Madan
Chris D. Shaw
Kevin Tang
and Gregory A. Dasch. 5. Preliminary Assessment of Genome Differences between the Reference Nine Mile Isolate and Two Human Endocarditis Isolates of Coxiella burnetii: Paul A. Beare
Stephen F. Porcella
Rekha Seshadri
James E. Samuel
and Robert A. Heinzen. 6. Fur-Regulated Genes in Coxiella burnetii: Heather L. Briggs
Mary J. Wilson
Rekha Seshadri
and James E. Samuel. 7. A Minimal Set of DNA Repair Genes Is Sufficient for Survival of Coxiella burnetii under Oxidative Stress: K Mertens
L Lantsheer
and J E Samuel. 8. Identification
Cloning
and Expression of Potential Diagnostic Markers for Q Fever: C C Chao
H W Chen
X Li
W B Xu
B Hanson
and W M Ching. 9. Preliminary Transcriptional Analysis of spoT Gene Family and of Membrane Proteins in Rickettsia conorii and Rickettsia felis: C Rovery
M V La
S Robineau
K Matsumoto
P Renesto
and D Raoult. 10. Phylogenic Analysis of Rickettsial Patatin-like Protein with Conserved Phospholipase A2 Active Sites: Guillaume Blanc
Patricia Renesto
and Didier Raoult. 11. Proteomic Analysis of Rickettsia prowazekii: C C Chao
D Chelius
T Zhang
E Mutumanje
and W M Ching. 12. Rickettsia conorii and R. prowazekii Proteome Analysis by 2DE-MS: A Step toward Functional Analysis of Rickettsial Genomes: Patricia Renesto
Saïd Azza
Alain Dolla
Patrick Fourquet
Guy Vestris
Jean-Pierre Gorvel
and Didier Raoult. 13. Phylogenetic Study of Rickettsia Species Using Sequences of the Autotransporter Protein-Encoding Gene sca2: Maxime Ngwamidiba
Guillaume Blanc
Hiroyuki Ogata
Didier Raoult
and Pierre-Edouard Fournier. 14. Molecular Characterization of a Group of Proteins Containing Ankyrin Repeats in Orientia tsutsugamushi: Nam-Hyuk Cho
Jo-Min Kim
Eun-Kyung Kwon
Se-Yoon Kim
Seung-Hoon Han
Hyuk Chu
Jung-Hee Lee
Myung-Sik Choi
and Ik-Sang Kim. 15. Ehrlichia ruminantium: A Promiscuous Genome: Maria Allsopp
Helena Steyn
Erich Zweygarth
and Basil Allsopp. Part II: Pathobiology of Q Fever Infection:. 16. Coxiella burnetii Infection: Jan Kazar. 17. Coxiella burnetii Whole Cell Lysate Protein Identification by Mass Spectrometry and Tandem Mass Spectrometry: Ludovit Skultety
Lenka Hernychova
Rudolf Toman
Martin Hubalek
Katarina Slaba
Jana Zechovska
Veronika Stofanikova
Juraj Lenco
Jiri Stulik
and Ales Macela. 18. Replication of Coxiella burnetii Is Inhibited in CHO K-1 Cells Treated with Inhibitors of Cholesterol Metabolism: Dale Howe and Robert A. Heinzen. 19. Protective Immunity against Q Fever Induced with a Recombinant P1 Antigen Fused with HspB of Coxiella burnetii: Qingfeng Li
Dongsheng Niu
Bohai Wen
Meiling Chen
Ling Qiu
and Jingbo Zhang. 20. Immunization Experiments with Recombinant Coxiella burnetii Proteins in a Murine Infection Model: Judith Tyczka
Sandra Eberling
and Georg Baljer. 21. Structural and Functional Characterization of the Glycan Antigens Involved in Immunobiology of Q Fever: Pavol Vadovic
Katarina Slaba
Marcela Fodorova
Ludovit Skultety
and Rudolf Toman. 22. Lack of Dendritic Cell Maturation Following Infection by Coxiella burnetii Synthesizing Different Lipopolysaccharide Chemotypes: Jeffrey G. Shannon
Dale Howe
and Robert A. Heinzen. 23. TLR2 Is Necessary to Inflammatory Response in Coxiella burnetii Infection: Soraya Meghari
Amélie Honstettre
Hubert Lepidi
Bernardt Ryffel
Didier Raoult
and Jean-Louis Mege. 24. Comparative Virulence of Phase I and II Coxiella burnetii in Immunodeficient Mice: Masako Andoh
Kasi E. Russell-Lodrigue
Guoquan Zhang
and James E. Samuel. 25. Balb/c Mouse Model and Real-Time Quantitative Polymerase Chain Reaction for Evaluation of the Immunoprotectivity against Q Fever: Jingbo Zhang
Bohai Wen
Meiling Chen
Jun Zhang
and Dongsheng Niu. 26. Hepatitis Associated with C. burnetii Isolates: K E Russell-Lodrigue
M W J Poels
G Q Zhang
D N Mcmurray
and J E Samuel. 27. Q Fever Research Group (QRG)
Adelaide: Activities-Exit Summary 1980-2004: B Marmion
R Harris
P Storm
K Helbig
I Penttila
D Worswick
and L Semendric. Part III: Pathobiology of Rickettsial Infection
Antibiotic Resistance
and Vaccines:. 28. Rickettsial Infections: Juan P. Olano. 29. The Presence of Eschars
but Not Greater Severity
in Portuguese Patients Infected with Israeli Spotted Fever: Rita De Sousa
Nahed Ismail
Sónia Dória-Nóbrega
Pedro Costa
Tiago Abreu
Ana França
Mário Amaro
Paula Proença
Paula Brito
José Poças
Teresa Ramos
Graça Cristina
Graça Pombo
Liliana Vitorino
Jorge Torgal
Fátima Bacellar
and David Walker. 30. Similarities and Differences in Host Cell Signaling following Infection with Different Rickettsia Species: Elena Rydkina
David J. Silverman
and Sanjeev K. Sahni. 31. Potential Roles for Regulatory Oxygenases in Rickettsial Pathogenesis: Sanjeev K. Sahni
Elena Rydkina
Abha Sahni
Suresh G. Joshi
and David J. Silverman. 32. Growth of Typhus Group and Spotted Fever Group Rickettsiae in Insect Cells: Tsuneo Uchiyama. 33. Genome Comparison Analysis of Molecular Mechanisms of Resistance to Antibiotics in the Rickettsia Genus: J M Rolain And D Raoult. 34. Cloning and Sequence Analysis of the 22-kDa Antigen Genes of Orientia tsutsugamushi Strains Kato
TA763
AFSC 7
18-032460
TH1814
and MAK 119: Hong Ge
Min Tong
Andrew Li
Rajan Mehta
and Wei-Mei Ching. 35. Nitric Oxide as a Mediator of Increased Microvascular Permeability during Acute Rickettsioses: Michael E. Woods
Gary Wen
and Juan P. Olano. 36. Cloning and Expression of 51-kDa Antigenic Protein of Neorickettsia risticii NR-JA1: Myeong-Kyu Park
Eun-Ha Kim
Mae-Rim Cho
Ying-Hua Yi
Mi-Jin Lee
Devendra H. Shah
Jin-Ho Park
Bae-Keun Park
Seong-Kug Eo
John-Hwa Lee
and Joon-Seok Chae. 37. Activity of Telithromycin against Thirteen New Isolates of C. burnetii Including Three Resistant to Doxycycline: Jean-Marc Rolain
Frédéric Lambert
and Didier Raoult. 38. Effect of Antibiotic Treatment in Patients with DEBONEL/TIBOLA: V Ibarra
J R Blanco
A Portillo
S Santibáñez
L Metola
and J A Oteo. 39. Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus: Marcela Fodorova
Pavol Vadovic
Ludovit Skultety
Katarina Slaba
and Rudolf Toman. 40. Analysis of Immunoprotectivity of the Recombinant OmpA of Rickettsia heilongjiangensis: Yanmei Jiao
Bohai Wen
Meiling Chen
Dongsheng Niu
Jun Zhang
and Ling Qiu. 41. Short- and Long-Term Immune Responses of CD-1 Outbred Mice to the Scrub Typhus DNA Vaccine Candidate: p47Kp: Guang Xu
Suchismita Chattopadhyay
Ju Jiang
Teik-Chye Chan
Chien-Chung Chao
Wei-Mei Ching
and Allen L. Richards. Part IV: Bartonella:. 42. Bartonellae as Elegant Hemotropic Parasites: Richard J. Birtles. 43. Production of Recombinant Protein Pap31 and Its Application for the Diagnosis of Bartonella bacilliformis Infection: A Taye
H Chen
K Duncan
Z Zhang
L Hendrix
J Gonzalez
and W Ching. 44. Bartonella bacilliformis GroEL: Effect on Growth of Human Vascular Endothelial Cells in Infected Cocultures: Laura S. Smitherman and Michael F. Minnick. 45. Occurrence of Bartonella henselae and Bartonella quintana among Human Immunodeficiency Virus-Infected Patients: M Pape
P Kollaras
K Mandraveli
A Tsona
S Metallidis
P Nikolaidis
and S Alexiou-Daniel. 46. Bacillary Angiomatosis Caused by Bartonella Quintana: Montserrat Sala
Bernat Font
Isabel Sanfeliu
Mariela Quesada
Imma Ponts
and Ferran Segura. 47. Molecular Screening of Bartonella Species in Rodents from the Russian Far East: Oleg Mediannikov
Leonid Ivanov
Nina Zdanovskaya
Nelya Vysochina
Pierre-Edouard Fournier
Irina Tarasevich
and Didier Raoult. 48. Characterization of Genes Involved in Long-Term Bacteremia in Mice by Bartonella birtlesii: Maria Mavris
Henri Saenz
Martine Monteil
Henri-Jean Boulouis
Christoph Dehio
and Muriel Vayssier-Taussat. Part V: New Rickettsiae or Rickettsiae Not Previously or Recently Known to Cause Human Infection:. 49. Rickettsia parkeri as a Paradigm for Multiple Causes of Tick-Borne Spotted Fever in the Western Hemisphere: Christopher D. Paddock. 50. Detection of a Typhus Group Rickettsia in Amblyomma Ticks in the State of Nuevo Leon
Mexico: Aaron Medina-Sanchez
Donald H. Bouyer
Virginia Alcantara-Rodriguez
Claudio Mafra
Jorge Zavala-Castro
Ted Whitworth
Vsevolod L. Popov
Ildefonso Fernandez-Salas
and David H. Walker. 51. Detection of a Non-Pathogenic Variant of Anaplasma phagocytophilum in Ixodes ricinus from La Rioja
Spain: A Portillo
A S Santos
S Santibáñez
L Pérez-Martínez
J R Blanco
V Ibarra
and J A Oteo. 52. Phylogenetic Analysis of a Novel Molecular Isolate of Spotted Fever Group Rickettsiae from Northern Peru: Candidatus Rickettsia andeanae: Ju Jiang
Patrick J. Blair
Vidal Felices
Cecilia Moron
Manuel Cespedes
Elizabeth Anaya
George B. Schoeler
John W. Sumner
James G. Olson
and Allen L. Richards. 53. Molecular and Biological Characterization of a Novel Coxiella-like Agent from Carios capensis: Will K. Reeves
Amanda D. Loftis
Rachael A. Priestley
William Wills
Felicia Sanders
And Gregory A. Dasch. 54. DEBONEL/TIBOLA: Is Rickettsia slovaca the Only Etiological Agent?: V Ibarra
A Portillo
S Santibáñez
J R Blanco
L Pérez-Martínez
J Márquez
And J A Oteo. 55. Low Risk of Developing Human Rickettsia aeschlimannii Infection in the North of Spain: J A Oteo
A Portillo
J R Blanco
V Ibarra
L Pérez-Martínez
C Izco
A Pérez-Palacios
and S Jiménez. 56. Novel Spotted Fever Group Rickettsiae (SFGR) Infecting Amblyomma americanum Ticks in Ohio
USA: D J Kelly
J R Carmichael
G C Booton
K F Poetter
And P A Fuerst. 57. Old and New Human Rickettsiosis in Minas Gerais State
Brazil: S B Calic
C M Barcellos-Rocha
R C Leite
C L Mafra
and M A M Galvão. 58. Ehrlichia ruminantium: An Emerging Human Pathogen?: M T E P Allsopp
M Louw
And E C Meyer. Part VI: Pathobiology of Ehrlichia and Anaplasma Infections:. 59. Anaplasma and Ehrlichia Infection: J Stephen Dumler. 60. The Interactions of Anaplasma phagocytophilum
Endothelial Cells
and Human Neutrophils: Michael J. Herron
Marna E. Ericson
Timothy J. Kurtti
and Ulrike G. Munderloh. 61. Balancing Protective Immunity and Immunopathology: A Unifying Model of Monocytotropic Ehrlichiosis: Nahed Ismail and David H. Walker. 62. Susceptibility and Resistance to Monocytic Ehrlichiosis in the Mouse: Gary M. Winslow
Constantine Bitsaktsis
and Eric Yager. 63. Overcoming Barriers to the Transformation of the Genus Ehrlichia: S Wesley Long
Ted J. Whitworth
David H. Walker
and Xue-Jie Yu. 64. Mechanisms of Immunological Control of Anaplasma phagocytophilum in Mice: Christina Rinkler
Yvonne Kern
Christian Bogdan
and Friederike D. Von Loewenich. 65. Platelet Dysfunction after Association with Anaplasma phagocytophilum in Vitro: Dori L. Borjesson
Jennifer L. Brazzell
and Regina Feferman. 66. Anaplasma phagocytophilum Infection Reduces Expression of Phagocytosis-Related Receptors on Neutrophils: Justin W. A. Garyu and J Stephen Dumler. 67. Analysis of Ehrlichial p28 Gene Expression in a Murine Model of Persistent Infection: Patricia A. Crocquet-Valdes
Jere W. Mcbride
Hui-Min Feng
Nahed Ismail
Melissa A. Small
Xue-Jie Yu
and David H. Walker. 68. Innate Immune Tissue Injury and Murine HGA: Tissue Injury in the Murine Model of Granulocytic Anaplasmosis Relates to Host Innate Immune Response and Not Pathogen Load: Diana G. Scorpio
Friederike D. Von Loewenich
Christian Bogdan
and J Stephen Dumler. 69. Cytokine Responses in Dogs Infected with Ehrlichia canis Oklahoma Strain: Tomoko Tajima and Yasuko Rikihisa. 70. Molecular Characterization of E. canis gp36 and E. chaffeensis gp47 Tandem Repeats among Isolates from Different Geographic Locations: C Kuyler Doyle
Ana Maria Cardenas
Daniel M. Aguiar
Marcelo B. Labruna
Lucy M. Ndip
Xue-Jie Yu
and Jere W. Mcbride. 71. Prophylactic Use of Sustained-Release Doxycycline Blocks Tick-Transmitted Infection by Anaplasma phagocytophilum in a Murine Model: Robert F. Massung
Nordin S. Zeidner
Marc C. Dolan
Dawn Roellig
Elizabeth Gabitzsch
Danielle R. Troughton
and Michael L. Levin. 72. Concentration of Procalcitonin and C-Reactive Protein in Patients with Human Granulocytic Anaplasmosis and the Initial Phase of Tick-Borne Encephalitis: Stanka Lotric-Furlan
Tereza Rojko
and Franc Strle. Part VII: Ricketsiae Agents of Bioterrorism:. 73. Genome Analysis of Coxiella burnetii Species: Insights into Pathogenesis and Evolution and Implications for Biodefense: Rekha Seshadri and James Samuel. 74. Attack Scenarios with Rickettsial Species: Implications for Response and Management: G Pappas
N Akritidis
and E V Tsianos. 75. The Pathogen Resource Integration Center: Implications for Rickettsial Research: Mark E. Hance
Michael J. Czar
Abdu Azad
Anjan Purkayastha
Eric E. Snyder
Oswald R. Crasta
Joao C. Setubal
and Bruno W. Sobral. 76. Evaluation of Low Concentration Aerosol for Infecting Humans with the Q Fever Pathogen: Eugene Vorobeychikov
Alexander Vasilenko
Nikolay Tokarevich
Ludmila Yakovleva
and Boris Nikolaev. Index of Contributors