RNA Nanotechnology

Herausgeber: Wang, Bin

• Gebundenes Buch

Produktbeschreibung

A comprehensive volume, this books details details the traditional approaches and the latest developments in the field of RNA-related technology. It targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications.

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Produktdetails

• Verlag: Taylor & Francis Ltd (Sales)
• Seitenzahl: 466
• Erscheinungstermin: 2. April 2014
• Englisch
• Abmessung: 236mm x 159mm x 32mm
• Gewicht: 794g
• ISBN-13: 9789814411646
• ISBN-10: 9814411647
• Artikelnr.: 38019992

Autorenporträt

Bin Wang obtained her Ph.D. from the Department of Chemistry at Queen's University (Canada). Her doctoral studies with Richard D. Oleschuk and J. Hugh Horton spanned the areas of analytical chemistry, nanotechnology, and surface chemistry, which involved developing polymer materials to fabricate microfluidic devices and further chemical modification of polymer surfaces for specific microfluidic applications. After finishing her Ph.D. study, Dr. Wang conducted a one-year postdoctoral research with P. Martin Petkovich at Queen's University to develop antigen- and antibody-modified polymer microdevices. In 2005, she joined Kevin M. Weeks' research group at the University of North Carolina at Chapel Hill. Her postdoctoral work involved applying the newly developed RNA structure-analyzing technology to monitor ligand-induced conformational changes in tRNAs and mRNAs. Dr. Wang's areas of interest are RNA biochemistry and nanotechnology.

Inhaltsangabe

Fundamental Aspects of RNA; Computational Approaches for Predicting RNA Structures; Traditional and Emerging Experimental Approaches for Probing RNA Structures
Including X-Ray Crystallography
Nuclear Magnetic Resonance (NMR) Spectroscopy
Enzymatic Cleavage
Chemical Probing
Nucleotide Analog Interference Mapping (NAIM)
In-Line Probing
Thermal Denaturation
and Single-Molecule Approaches; The Design and Construction of RNA-Based Nanostructures; The Potential Biological and Therapeutic Applications of Small RNA Molecules Such as Small/Short Interfering RNAs (siRNAs)
MicroRNAs (miRNAs)
RNA Aptamers
and Ribozymes; Alternative Splicing; RNA Motifs for Sensing Metal Ions.