Rodovia dos Tamoios (official designation SP-099) is a highway in the Brazilian state of São Paulo. The highway is partly dual-lane, part single-lane, and runs from the city of São José dos Campos, located in the Paraíba River valley in the upper plateau of São Paulo down the Serra do Mar to the coastal lowlands of the city of Caraguatatuba, connecting to the Rodovia Rio-Santos (federal highway). As such, it is part of a series of Serra do Mar highways which include Rodovia Anchieta (SP-150) and Rodovia dos Imigrantes (SP-160), departing from São Paulo, the Mogi das Cruzes-Bertioga highway, and the Taubaté-Ubatuba highway.