Dentin adhesive systems have created a new era in the field of dentistry. Owing to its property of adherence to the tooth structure by both micromechanical and chemical means, it finds a wide range of application in various fields.The current trend in the development of dentin adhesives attempts to simplify bonding steps and make them more user-friendly Advances in different scientific disciplines will enrich the pool from which ideas may be drawn in designing future dental adhesives.