Role of angiogenic markers in the genesis of preeclampsia - AKSAS, Kahina
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Pre-eclampsia (PE) is a worldwide public health problem, a disease of placental origin affecting the maternal endothelium. It is classically defined as de novo hypertension associated with proteinuria > 0.3 g/24 h occurring after 20 weeks of gestation and is characterized by a latent phase between the beginning of pregnancy and the onset of the disease. This opens the way to a possible screening which would allow an early management of parturients in order to reduce the complications related to this pathology.The main goal of this work is to evaluate the interest of the determination of…mehr

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Produktbeschreibung
Pre-eclampsia (PE) is a worldwide public health problem, a disease of placental origin affecting the maternal endothelium. It is classically defined as de novo hypertension associated with proteinuria > 0.3 g/24 h occurring after 20 weeks of gestation and is characterized by a latent phase between the beginning of pregnancy and the onset of the disease. This opens the way to a possible screening which would allow an early management of parturients in order to reduce the complications related to this pathology.The main goal of this work is to evaluate the interest of the determination of angiogenic biomarkers (sFlt1 and PLGF) in the detection of preeclampsia in the first and second trimester of pregnancy. The prognostic value of PAPP-A, AFP, and free-betaHCG in the occurrence of PE was also analyzed.
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Autorenporträt
Pr AKSAS Kahina est professeur Hospitalo-universitaire de Biochimie au sein des facultés de Pharmacie et de médecine de l'Université Alger-1. Elle exerce aussi son métier au niveau du laboratoire central de Biologie du CHU Bab El Oued ou elle est chef d'unité de Biochimie et maitre de stage des internes en Pharmacie.