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Fluid therapy plays an important role in achieving optimal outcomes after surgery and it continues to be one of the most controversial aspects of perioperative care. The aims of perioperative fluid administration are to avoid dehydration, to maintain an effective circulating volume, and to prevent inadequate tissue perfusion during a period when the patient is unable to achieve these goals through normal oral fluid intake. Knowledge of the effects of different fluids has increased in recent years, and the choice of fluid in a variety of clinical situations can now be rationally guided. Through this book it has been tried to review the composition of different crystalloid fluids, potential pathophysiological responses following crystalloid fluid infusion and put up the effectiveness of various crystalloid fluids.