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Coronary heart disease (CHD) is the most urgent problem of cardiology due to its high prevalence and high risk of cardiovascular complications and death. A significant role in the development of atherosclerosis and the resulting CHD belongs to immunoinflammatory reactions, potential proinflammatory factors include oxidized lipids and proinflammatory cytokines. In this connection, the evaluation of immunoinflammatory reactions peculiarities at different course of angina pectoris to establish diagnostic and prognostic value of inflammatory markers in CHD patients seems to be actual.