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Schizophrenia is a chronic, severe mental illness. The disease characterized by disturbed form and content of thoughts affects approximately 1% of the population. A goal of the current investigation was to alleviate the adverse effects of neuroleptics on motor behavior. The results of study indicates that serotonergic system, and particularly 5-HT-1A and 5-HT-2A/2C receptors, may be involved in the treatment of EPS induced by typical neuroleptics. It is suggested that serotonergic compounds with antidepressant activity may be of use for extending therapeutics in schizophrenia. The findings may…mehr

Produktbeschreibung
Schizophrenia is a chronic, severe mental illness. The disease characterized by disturbed form and content of thoughts affects approximately 1% of the population. A goal of the current investigation was to alleviate the adverse effects of neuroleptics on motor behavior. The results of study indicates that serotonergic system, and particularly 5-HT-1A and 5-HT-2A/2C receptors, may be involved in the treatment of EPS induced by typical neuroleptics. It is suggested that serotonergic compounds with antidepressant activity may be of use for extending therapeutics in schizophrenia. The findings may help to develop antipsychotic agents with an improved therapeutic and smaller side effect profile.
Autorenporträt
Erum Shireen trabaja actualmente como profesora adjunta en la Universidad de Karachi. Terminó su doctorado en 2010 en el Departamento de Bioquímica de la Universidad de Karachi. Obtuvo las medallas de oro "Izaz-e-Sabqat", "SubRang" y "Zaidi Abid" del Premio Presidencial por sus sobresalientes calificaciones académicas a nivel de Máster en 2003.