This book based on thesis is devoted to developing automatic control of a cargo mobile robot, which includes a manipulator with six degrees of freedom, and a mobile platform based on the rover with six actively controlled wheels, which provides mobility, allows to move easily on the rocky or sandy terrain and up and down stairs, as well as increases the level of stability in different conditions of movement. Modelling and experimental methods were used to develop a semi-automated control system to overcome the mobility and stability issues caused by a number of factors, including design flaws, problems with component manufacture and errors in sketch modelling when creating the robotics design plan. And, to create an automatic control for a cargo mobile robot which involves the use of a control system that allows the robot to move, avoid obstacles and correctly perform the specified tasks for the lifting arm. This project presents the design of automatic control of a cargo robot with a platform based on a rover with a manipulator which can be used to automate cargo transportation in various environments where a high degree of accuracy and reliability is required.