High Quality Content by WIKIPEDIA articles! Sackville Street can refer to either a street in Manchester city centre, England, or to a large, historic college building on that street.Sackville Street is a street in Manchester city centre. It runs in a northwest-southeast direction and is split into two sections by Whitworth Street, which runs in a northeast-southwest direction. At the northern end of the street is a junction with Portland Street. The northern half of the street runs through Manchester's Gay Village and past Chorlton Street Coach Station.