Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Safe (sometimes written as [safe] or [SAFE]) is a 1995 drama/thriller film written and directed by Todd Haynes, and produced by Christine Vachon. It was voted the best film of the 1990s in the 1999 Village Voice Film Poll.Set in an affluent neighbourhood of the San Fernando Valley in 1987, the film recounts the life of a seemingly unremarkable homemaker, Carol White (Julianne Moore) who develops multiple chemical sensitivity (MCS, also known as "Twentieth-Century Disease"). MCS is a medically controversial diagnosis in which a person develops mild to severe non-specific symptoms and believes that these symptoms are triggered by chemicals found in everyday household and industrial products.