E. Hodgson

Safer Insecticides Development and Use

Development and Use

• Gebundenes Buch

Produktbeschreibung

Reference to the design of new insecticides nontoxic to the environment and the public emphasizing optimal food production with greater safety. Some 30 international experts examine topics including new types of active molecules among natural products and animal toxins; insect metabolic and organ sy

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 612
• Erscheinungstermin: 27. April 1990
• Englisch
• Abmessung: 235mm x 157mm x 40mm
• Gewicht: 1133g
• ISBN-13: 9780824778842
• ISBN-10: 0824778847
• Artikelnr.: 22100676

Autorenporträt

ERNEST HODGSON is William Neal Reynolds Professor and head of the Department of Toxicology at North Carolina State University, Raleigh. The author of over 200 research articles and editor of almost 20 books, he is a member of the Society of Toxicology, American Society for Pharmacology and Experimental Therapeutics, American Chemical Society, International Society for the Study of Xenobiotics, Society for Environmental Toxicology and Chemistry, and Sigma Xi. Dr. Hodgson received the B.S. degree (1954) from Kings College, University of Durham, England, and Ph.D. degree (1960) from Oregon State University, Corvallis. RONALD J. KUHR is Associate Dean of the College of Agriculture and Life Sciences and Director of the North Carolina Agricultural Research Service at North Carolina State University, Raleigh. The author or coauthor of almost 40 research papers and coeditor of four books, he is a member of the Entomological Society of America, American Chemical Society, North Carolina Entomological Society, Sigma Xi, and Gamma Sigma Delta. Dr. Kuhr received the B.S. degree (1963) from the University of WisconsinMadison, and Ph.D. degree (1966) from the University of California, Berkeley.

Inhaltsangabe

Preface
Contributors
1. Introduction /Ernest Hodgson and Ronald J. Kuhr
I. Introduction
II. Factors Involved in Insecticide Development
III. Approaches to the Development of Safer Insecticides
IV. Summary and Conclusions
2. Metabolism of Xenobiotics /W. C. Dauterman and Ernest Hodgson
I. Introduction
II. Phase
I Reactions
III. Phase
II Reactions
IV. Nutritional Effects on Xenobiotic Metabolism
V. Physiological Effects on Xenobiotic Metabolism
VI. Genetic Effects on Xenobiotic Metabolism
VII. Chemical Effects on Xenobiotic Metabolism
3. Quantitative Structure
Activity Relationships of Insecticides /Keiichiro Nishimura, Haiime lwamura, and Toshio Fuiita
I. Introduction
II. Quantitative Analysis of Structure
Activity Relationships
III. Approaches Toward Safer Insecticides
IV. Concluding Remarks
4. Endocrine
Based Insecticides /Thomas C. Sparks
I. Introduction
II. Physiological Approaches to Insecticide Selectivity
III. Approaches to Discovering New Insecticides
IV. Exploiting the Insect Endocrine System
V. Endocrine
Based Insecticides: Potential Modes of Action
VI. Conclusions
5. Nervous
System
Based Insecticides /Mohyee E. Eldefrawi and Amira T. Eldefrawi
I. Introduction
II. Voltage
Dependent Ion Channels
III. Neurotransmitter Receptors
IV. Neurotransmitter Synthesis and Release
V. Termination of Neurotransmitter Action
VI. Concluding Remarks
6. Insecticides Based on Differences in Metabolic Pathways /Richard T. Mayer, G. Cunningham, and J. Gupton
I. Introduction
II. Chitin Synthesis Inhibitors
III. Prostaglandins
IV. Steroid Analogs as Insect Molting Hormone Inhibitors
V. Conclusions
7. Inducers of Plant Resistance to Insects /Daniel C. Fischer, Marcos Kogan, and Patrick Greany
I. Introduction
II. Inducers of Plant Resistance or Susceptibility Against Insects
III. Induction of Resistance by Growth Regulators, Plant Hormones, and Herbicides
IV. Induction of Resistance by Previous Herbivory
V. Potential Uses of Induced Resistance in Pest Management
VI. Induced Resistance and Pest Management
8. Proinsecticides: Metabolically Activated Toxicants /Glenn D. Prestwich
I. Fundamental Prodrug Concepts
II. Proinsecticides as Prodrugs
III. A Compendium of Proinsecticides
IV. Future Design Strategies
9. Natural Products from Plants for the Control of Insect Pests /E. Arthur Bell, Linda E. Fellows, and
Monique S. J, Simmonds
I. Introduction
II. Plant
Based Insecticides
III. The Search for New Products
IV. Toxins vs. Deterrents
V. Insect Perception of Secondary Compounds
VI. Plant Variability and Resistance to Insect Predation
VII. Acquired Tolerance of Antiinsect Compounds in Specialist Feeders
VIII. Conclusions
10. Viruses and Bacteria as Sources of Insecticides /C. Y. Kawanishi and C. A. Held
I. Introduction
II. Microbial Properties that Affect Pesticidal Use
III. Viruses
IV. Bacteria
V. Biotechnology and the Future of Microbial Pesticides
VI. Conclusions
11. Spider Toxins as Lead Structures for Novel Pesticides /Donald L. J. Quicke and Peter N. R. Usherwood
I. Introduction
II. Spider Taxonomy, Biology, and Toxinology
III. Isolation and Chemical Characterization of Araneid Venoms
IV. Neurophysiological Effects of Araneid
Spider Venoms
V. Conclusions
12. An Integrated Approach for Improvements in Application Technology /Franklin R. Hall
I. Introduction
II. Exposure Potentials with the Use of Agrichemicals
III. Trends and Developments in Application Technology
IV. Physics of Application
V. Biological Requirements
VI. Crop Protection Technology
VII. Prospectus
VIII. Future Needs
IX. Conclusions
13. Improved Safety Through Reduction in Use of Existing Chemicals /A. M. Agnello and J. R. Bradley, Jr.
I. Introduction
II. Pesticide Reduction as a Result of New Approaches
III. Pesticide Reduction as a Result of New Chemistry
IV. Summary
14. Safety Considerations Relating to the Manufacture of Agrichemicals in the U.S. and the Third World Gustave /K. Kohn and Stephen J. Raab
I. Introduction
II. The Decision to Manufacture
III. Cost
Benefit Analysis
IV. Analytical Equipment and Its Upkeep
V. Alternatives for Methyl Isocyanate and Phosgene
VI. Chemical Aspects of Risk Reduction for the Manufacture of Carbamates (Urethanes)
VII. Summary
15. Challenges: The Industrial Viewpoint /J. F. Engel, W. N. Harnish, and C. A. Staetz
I. Introduction
II. Market Considerations
III. Industry Approaches
IV. Constraints
V. The Future
Index.