This book covers distribution and partitioning of toxic metals Lead (Pb), Cadmium (cd), Chromium (Cr) and Copper (Cu) in water, sediments and trophic transfer in Lake Victoria, Kenya with a view of discerning the human epidemiological effects on consumption of three leading commercial fish species in Lake Victoria, Kenya waters.Toxicity of Pb, Cd, Cr and Cu trace metals in Lake Victoria did not exceed the surface water quality guideline levels as prescribed by World Health Organization (WHO) and Food and Agricultural Organization (FAO) of the United Nations to protect fresh water organisms.Trace elements in Lake Victoria's three leading commercial fish species viz Rastrineobola argentea, Oreochromis niloticus and Late niloticus were found to be within safe limits of WHO and FAO and to be safe for human consumption.