Biomarkers has always been an enigma of interest for researchers. The information they carry and if revealed and understood by the researchers will generate an array of hope and answers from diagnosis of the rarest of rare diseases and their cure. Body fluids like blood, urine and cerebro spinal fluid have playing a significant role as a storehouse of various biomarkers. The role of saliva as a biomarker has not been dealt with such enthusiasm in the past though it continues to nurture numerous biomarkers that plays a key role in the identification of systemic as well as oral diseases. This book illustrates on the various biomakers found in saliva and their potential in the diagnosis and treatment of various diseases.