Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Satoyoshi syndrome, also known as Komuragueri syndrome, is a rare progressive disorder of presumed autoimmune etiology, characterized by painful muscle spasms, alopecia, diarrhea, endocrinopathy with amenorrhoea and secondary skeletal abnormalities. The syndrome was first reported in 1967 by Eijito Satoyoshi and Kaneo Yamada in Tokyo, Japan. To this date, less than 40 cases worldwide have been reported for the Satoyoshi syndrome.