Palimpsest of readings and writings, aims to generate a dialogue of ideas on the problem of science and ideology in the formation of knowledge. Understanding the role of the dominant ideology of the capitalist system in the discourse of science and in the construction of societies. We respond to an old dialogue regarding the role of modern science as an institution and discourse, in the conformation of capitalism, in Colombia in particular, in Latin America as a region; and in general in all countries that suffered or suffer from the colonial system without having resolved the progress and development promised by modernity.