Ionut David

Scientific Curves Analysis Software

Bioinformatics

• Broschiertes Buch

Produktbeschreibung

All biological processes, also those involving membrane proteins, are steered by molecular interactions. Molecular interactions guide the folding and stability of membrane proteins, determine their assembly, switch their functional states or mediate signal transduction. The sequential steps of molecular interactions driving these processes can be described by dynamic energy landscapes. The conceptual energy landscape allows to follow the complex reaction pathways of membrane proteins, while its modifications describe why and how pathways are changed. Single-molecule force spectroscopy (SMFS) detects, quantifies and locates within the energy landscape changes of proteins. SMFS is a technique which measures the force necessary to unfold a protein. This is applicable for both globular and membrane proteins. The resulting force-distance curves contain valuable information on the protein structure, conformation, and inter- and intra-molecular forces. For analysis of the force-distancecurves a lot of software tools were developed. An evaluation of software tools used for scientific curve analysis software is very important to make sure the events are correctly detected.

Produktdetails

• Verlag: GlobeEdit
• Seitenzahl: 104
• Erscheinungstermin: 15. September 2014
• Englisch
• Abmessung: 220mm x 150mm x 7mm
• Gewicht: 174g
• ISBN-13: 9783639630046
• ISBN-10: 3639630041
• Artikelnr.: 41593240

Autorenporträt

Ionut David received a B.Sc. in computer science from ¿Alexandru Ioan Cuzä University of Iasi, Romania and a M.Sc. in computational engineering from Technical University of Dresden, Germany. Since February 2010, he is a Ph.D. candidate in the System Architecture and Networking (SAN) Group at Eindhoven University of Technology, The Netherlands.