Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A…mehr
Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included.
The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Part 1 Introduction and front matter 1. Plastic surgery, fat, and fat plasticity: How adipose tissue changed the landscape of stem cell therapeutics Lauren Kokai and J. Peter Rubin Part 2 Basic biology of adipose stem cells 2. Developmental origins of adipocytes: What we learn from human pluripotent stem cells Xi Yao, Vincent Dani, and Christian Dani 3. Establishing the adipose stem cell identity: Characterization assays and functional properties Mark A.A. Harrison, Sara I. Al-Ghadban, Benjamen T. O'Donnell, Omair A. Mohiuddin, Rachel M. Wise, Brianne N. Sullivan, and Bruce A. Bunnell 4. Insights into the adipose stem cell niche in health and disease Aaron C. Brown 5. Mechanisms of adipose-derived stem cell aging and the impact on therapeutic potential Xiaoyin Shan and Ivona Percec 6. Human pluripotent nontumorigenic multilineage differentiating stress enduring (Muse) cells isolated from adipose tissue: A new paradigm in regenerative medicine and cell therapy Karen L. Leung and Gregorio D. Chazenbalk 7. Adipose stem cell homing and routes of delivery Ganesh Swaminathan, Yang Qiao, Bhavesh D. Kevadiya, Lucille A. Bresette, Daniel D. Liu, and Avnesh S. Thakor 8. Bioreactors and microphysiological systems for adipose-based pharmacologic screening Mallory D. Griffin and Rosalyn D. Abbott Part 3 Adipose cell therapy and regenerative medicine 9. Adipose stem cells and donor demographics: Impact of anatomic location, donor sex, race, BMI, and health Adam Cottrill, Yasamin Samadi, and Kacey G. Marra 10. Immunomodulatory properties of adipose stem cells in vivo: Preclinical and clinical applications Matthias Waldner, Fuat Baris Bengur, and Lauren Kokai 11. Clinical experience with adipose tissue enriched with adipose stem cells Shawn Loder, Danielle Minteer, and J. Peter Rubin 12. Adipose-derived stem cells for wound healing and fibrosis Y Samadi, FM Egro, RL Rodriguez, and A Ejaz 13. Oncologic safety of adipose-derived stem cell application Hakan Orbay and David E. Sahar 14. FDA regulation of adipose cell use in clinical trials and clinical translation Mary Ann Chirba, Veronica Morgan Jones, Patsy Simon, and Adam J. Katz Part 4 Engineering with adipose stem cell 15. Biomaterial control of adipose-derived stem/stromal cell differentiation John Walker and Lauren Flynn 16. Genetic modification of adipose-derived stem cells for bone regeneration Harsh N. Shah, Abra H. Shen, Sandeep Adem, Ankit Salhotra, Michael T. Longaker, and Derrick C. Wan 17. Adipose-derived stromal/stem cells for bone tissue engineering applications Nathalie Faucheux, Fabien Kawecki, Jessica Jann, Franc¸ois A. Auger, Roberto D. Fanganiello, and Julie Fradette 18. The hematopoietic potential of stem cells from the adipose tissue Beatrice Cousin and Louis Casteilla 19. Adipose stem cells for peripheral nerve engineering Benjamin K. Schilling, George E. Panagis, Jocelyn S. Baker, and Kacey G. Marra
Part 1 Introduction and front matter 1. Plastic surgery, fat, and fat plasticity: How adipose tissue changed the landscape of stem cell therapeutics Lauren Kokai and J. Peter Rubin Part 2 Basic biology of adipose stem cells 2. Developmental origins of adipocytes: What we learn from human pluripotent stem cells Xi Yao, Vincent Dani, and Christian Dani 3. Establishing the adipose stem cell identity: Characterization assays and functional properties Mark A.A. Harrison, Sara I. Al-Ghadban, Benjamen T. O'Donnell, Omair A. Mohiuddin, Rachel M. Wise, Brianne N. Sullivan, and Bruce A. Bunnell 4. Insights into the adipose stem cell niche in health and disease Aaron C. Brown 5. Mechanisms of adipose-derived stem cell aging and the impact on therapeutic potential Xiaoyin Shan and Ivona Percec 6. Human pluripotent nontumorigenic multilineage differentiating stress enduring (Muse) cells isolated from adipose tissue: A new paradigm in regenerative medicine and cell therapy Karen L. Leung and Gregorio D. Chazenbalk 7. Adipose stem cell homing and routes of delivery Ganesh Swaminathan, Yang Qiao, Bhavesh D. Kevadiya, Lucille A. Bresette, Daniel D. Liu, and Avnesh S. Thakor 8. Bioreactors and microphysiological systems for adipose-based pharmacologic screening Mallory D. Griffin and Rosalyn D. Abbott Part 3 Adipose cell therapy and regenerative medicine 9. Adipose stem cells and donor demographics: Impact of anatomic location, donor sex, race, BMI, and health Adam Cottrill, Yasamin Samadi, and Kacey G. Marra 10. Immunomodulatory properties of adipose stem cells in vivo: Preclinical and clinical applications Matthias Waldner, Fuat Baris Bengur, and Lauren Kokai 11. Clinical experience with adipose tissue enriched with adipose stem cells Shawn Loder, Danielle Minteer, and J. Peter Rubin 12. Adipose-derived stem cells for wound healing and fibrosis Y Samadi, FM Egro, RL Rodriguez, and A Ejaz 13. Oncologic safety of adipose-derived stem cell application Hakan Orbay and David E. Sahar 14. FDA regulation of adipose cell use in clinical trials and clinical translation Mary Ann Chirba, Veronica Morgan Jones, Patsy Simon, and Adam J. Katz Part 4 Engineering with adipose stem cell 15. Biomaterial control of adipose-derived stem/stromal cell differentiation John Walker and Lauren Flynn 16. Genetic modification of adipose-derived stem cells for bone regeneration Harsh N. Shah, Abra H. Shen, Sandeep Adem, Ankit Salhotra, Michael T. Longaker, and Derrick C. Wan 17. Adipose-derived stromal/stem cells for bone tissue engineering applications Nathalie Faucheux, Fabien Kawecki, Jessica Jann, Franc¸ois A. Auger, Roberto D. Fanganiello, and Julie Fradette 18. The hematopoietic potential of stem cells from the adipose tissue Beatrice Cousin and Louis Casteilla 19. Adipose stem cells for peripheral nerve engineering Benjamin K. Schilling, George E. Panagis, Jocelyn S. Baker, and Kacey G. Marra
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