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Soil salinity has become a problem of great concern to the environment and is expanding very rapidly throughout the world. It is highly essential to test some important medicinal plants for their salinity tolerance so that, such plants can be tried for their growth in such saline soils, which have become rather useless for most of these crops. Therefore It is also essential to understand the mechanisms underlying this phenomenon. Keeping this view in mind, in the present investigation an attempt has been made to study the physiology of salt tolerance in the promising medicinal plant Tribulus terrestris. There is a very little work on medicinal plants. Most of the medicinal plants have been studied for their content of medicinal component. There are a few attempts to study the physiological aspects of the plant. In the present investigation Tribulus terrestris L. is the medicinal plant growing in the field as common weed but having several medicinal properties embodied in them. Particularly those associated with urinary problems, also to control cough, asthma, skin-heart diseases and as a sex enhancer, have been studied for their physiology and biochemistry. w. r. t. salt stress.