High Quality Content by WIKIPEDIA articles! sec-Butyl acetate, or s-butyl acetate, is a solvent commonly used as a solvent in lacquers and enamels, where it is used in the production of acyclic polymers, vinyl resins, and nitrocellulose. It is a clear flammable liquid with a sweet smell. sec-Butyl acetate has three isomers: n-butyl acetate, isobutyl acetate, and tert-butyl acetate. The first method of production of sec-butyl acetate was the esterification of sec-butanol and acetic anhydride. It was experimentally determined and published in 1946 by Rolf Altschul. The LD50 for rats is 13 g/kg. Exposure in humans to significant quantities of sec-butyl acetate can cause irritation to the eyes, mouth, throat, nose, and skin. Ingestion and inhalation of sec-butyl acetate can cause central nervous system depression producing symptoms of dizziness and disorientation.