Secondary Hyperparathyroidism in Haemodialysis Patients - Khan, Samreen;Malik, Husna;Khan, Iahtasham
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Secondary hyperparathyroidism (SHPT) develops frequently in patients with "End Stage Renal Disease" because the production of 1, 25 (OH) 2- vitamin D (calcitriol) decreases in the kidneys. That's why patients may develop osteodystrophy or osteomalacia. The functional role of vitamin D3 under normal body condition is to regulate secretion of parathyroid hormone (PTH) synthesis and release. Parameters such as calcium, phosphate and vitamin D3 act upon PTH. In normal subjects, the homeostasis of these parameters is strongly interconnected but in renal failure, the metabolism of each of these…mehr

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Produktbeschreibung
Secondary hyperparathyroidism (SHPT) develops frequently in patients with "End Stage Renal Disease" because the production of 1, 25 (OH) 2- vitamin D (calcitriol) decreases in the kidneys. That's why patients may develop osteodystrophy or osteomalacia. The functional role of vitamin D3 under normal body condition is to regulate secretion of parathyroid hormone (PTH) synthesis and release. Parameters such as calcium, phosphate and vitamin D3 act upon PTH. In normal subjects, the homeostasis of these parameters is strongly interconnected but in renal failure, the metabolism of each of these parameters may be deregulated. The diseased kidney is unable to produce vital hormone that is called erythropoietin which increases synthesis of red blood cells. The anemic condition is seen in CKD (chronic kidney disease) because erythropoietin production become reduced. In Pakistan, CKD patients are continuously increasing annually. We conducted a blood and serosurvey study in Lahore metropolitan city of Punjab, Pakistan to see the co-relation between SHPT and CKD. This epidemiological research of public health will be beneficial for onward broad demographic surveillance programs.
Autorenporträt
I did my MS Zoology in 2011 from Lahore College for Women University, Lahore, Pakistan. My areas of interest are physiology and haematology. I would like to continue my research in chronic renal failure. I also contributed as an active member in international conference on ¿Sustainable approaches for pest and vector control management" in Pakistan.