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The present investigation was performed to evaluate the effect of acid pretreatment, bonding condition (wet or dry dentin) and the application technique (single application or double application)on resin/dentin bond strength and the morphology of the resin/dentin interface using two self-etching adhesive systems. The results showed that the type of the adhesive had a significant effect on the resin/dentin shear bond strength, followed by dentin condition.