The International Labour Office describes domestic work as one of the most problematic sectors, not only because of unfavourable working conditions but also because of physical, psychological and sexual violence. Yet the existing literature remains deeply marked by a lack of information on the sexual and reproductive health of domestic workers. The aim of this study, which is intended to contribute to improving the sexual and reproductive health of girls in domestic service, is to describe the knowledge, attitudes, practices and preventive sexual behaviour adopted by these girls. The study showed that the reproductive health of adolescent girls and young women in domestic service in Dakar is characterised by relatively extreme vulnerability, due on the one hand to their profession, but also and above all to their low level of knowledge of RH prevention methods. The unfavourable attitudes towards these methods and the social perception of the sexuality of adolescent girls in Senegal weigh heavily on their use of these reproductive health prevention methods.