The world is facing a problem of enormous epidemiological relevance: sexually transmitted infections and these depend largely on human behavior. In 2018, a quasi-experimental intervention study was conducted with a group, with the aim of determining the influence of an educational program on Sexually Transmitted Infections in adolescents of the consultory # 2 of the Policlinico Manuel Piti Fajardo, of the 96 young people dispensed selected 87, by non-probabilistic demonstrated by criterion. The study consisted of three stages: a diagnostic stage in which a survey was applied to evaluate previous knowledge on the subject, an intervention stage in which the educational program was implemented, and a final evaluation stage to corroborate the effectiveness of the intervention. The data were collected in a spreadsheet designed by the author and were presented in tables, using the percentage as the unit of measurement and the Chi-square and Student's t-test as statistical validation tests.