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Surgical resection and radiofrequency ablation in treatment of hepatocellular carcinoma are different modalities for treatment of hepatocellular carcinoma. The aim of this study was to evaluate the surgical liver resection in comparison with radiofrequency in treatment of early HCC regarding intraoperative blood loss and transfusion, time of respectability, time of operation, ICU stay, and hospital stay, postoperative morbidity, mortality and overall survival.