Single Transverse Palmar Crease
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High Quality Content by WIKIPEDIA articles! In humans, a single transverse palmar crease is a single crease that extends across the palm of the hand, formed by the fusion of the two palmar creases that people typically have. Because it resembles the usual condition of non-human simians, it is also known as a simian crease or simian line, although these terms have fallen out of favor due to its pejorative connotation.The presence of a single transverse palmar crease can be, but is not always, a symptom associated with abnormal medical conditions, such as Fetal alcohol syndrome, or with genetic…mehr

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High Quality Content by WIKIPEDIA articles! In humans, a single transverse palmar crease is a single crease that extends across the palm of the hand, formed by the fusion of the two palmar creases that people typically have. Because it resembles the usual condition of non-human simians, it is also known as a simian crease or simian line, although these terms have fallen out of favor due to its pejorative connotation.The presence of a single transverse palmar crease can be, but is not always, a symptom associated with abnormal medical conditions, such as Fetal alcohol syndrome, or with genetic chromosomal abnormalities, including Down syndrome (chromosome 21), cri du chat syndrome (chromosome 5), Noonan syndrome (chromosome 12), Patau syndrome (chromosome 13), Edward's syndrome (chromosome 18), and Aarskog-Scott syndrome (X-linked recessive). Bilateral or unilateral single palmar creases are also associated with aberrations on chromosome 9.