"Elucidates the research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities Summarizes the multidiscipline views and publications on this diverse topic, covering cell development, cardiovascular and pulmonary systems, neurodegenerative disorders, cancer and metabolism"--
"Elucidates the research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities Summarizes the multidiscipline views and publications on this diverse topic, covering cell development, cardiovascular and pulmonary systems, neurodegenerative disorders, cancer and metabolism"--
Section I: Sirtuins, neurodegenerative disease, lifespan extension, and aging 1. Novel treatment strategies for neurodegenerative disease with sirtuins Kenneth Maiese 2. NAD1: a crucial regulator of sirtuin activity in aging Nady Braidy And Maria Villalva (D.) 3. Sirtuins and life span extension Shin-Hae Lee and Kyung-Jin Min 4. Sirtuins and aging Brian J. Morris 5. Sirtuins in the biology of aging Mateusz Watroba And Dariusz Szukiewicz 6. Sirtuins as regulators and the regulated molecules of exosomes Qing Han, Yirui Cheng, and Weiliang Xia 7. Sirtuins in aging, age-related pathologies and their association with circadian rhythm Sankarathi Balaiya 8. Sirtuins, mitochondria, and the melatonergic pathway in Alzheimer's disease G. Anderson and M. Maes 9. Sirtuins, melatonin, and the relevancevof circadian oscillators Rüdiger Hardeland 10. Epigenetic role of sirtuins in neurodegenerative brain disorders Archita Khanna, Anamika, and Surendra Kumar Trigun 11. Sirtuins and stem cell maintenance, proliferation, and differentiation Ryan A. Denu and Peiman Hematti 12. Sirtuins in mechanistic target of rapamycin complex 1 signaling J. Burillo, P. Marqués, B. Jiménez, C. González-Blanco, M. Benito, and C. Guillén 13. Free-radical redox timer, sirtuins and aging: from chemistry of free radicals to systems theory of reliability Vitaly K. Koltover and Tatjana A. Skipa 14. Sirtuins, mitochondria, and exercise in health and disease Anibh M. Das and Partha Dabke Section II: Sirtuins, cardiovascular disease and end-organ disease 15. Scope to develop sirtuins modulators as a therapy to attenuate cardiac complications Bugga Paramesha and Sanjay K. Banerjee 16. Role of sirtuins in cardiovascular diseases Venkatraman Ravi, Sneha Mishra, and Nagalingam Ravi Sundaresan 17. Targeting sirtuins to modulate energy metabolism in heart disease Tsunehisa Yamamoto and Ken Shinmura 18. Sirtuin 1 mediates hepatoprotective effects of resveratrol-like compounds in experimental liver injury Hassan Farghali, Mighty Kgalalelo Kemelo, and Nikolina Kutinová Canová 19. Sirtuins as key players in aging and kidney dysfunction Luca Perico and Ariela Benigni 20. Role of sirtuins in liver diseases D. Ezhilarasan and M. Najimi 22. Vitagenes in avian biology: protective functions of sirtuins Peter F. Surai, Ivan I. Kochish, and Vladimir I. Fisinin 23. Sirtuins in hematopoiesis and blood malignancies Berta N. Vazquez, Irene Fernández-Duran, and Alejandro Vaquero Index
Section I: Sirtuins, neurodegenerative disease, lifespan extension, and aging 1. Novel treatment strategies for neurodegenerative disease with sirtuins Kenneth Maiese 2. NAD1: a crucial regulator of sirtuin activity in aging Nady Braidy And Maria Villalva (D.) 3. Sirtuins and life span extension Shin-Hae Lee and Kyung-Jin Min 4. Sirtuins and aging Brian J. Morris 5. Sirtuins in the biology of aging Mateusz Watroba And Dariusz Szukiewicz 6. Sirtuins as regulators and the regulated molecules of exosomes Qing Han, Yirui Cheng, and Weiliang Xia 7. Sirtuins in aging, age-related pathologies and their association with circadian rhythm Sankarathi Balaiya 8. Sirtuins, mitochondria, and the melatonergic pathway in Alzheimer's disease G. Anderson and M. Maes 9. Sirtuins, melatonin, and the relevancevof circadian oscillators Rüdiger Hardeland 10. Epigenetic role of sirtuins in neurodegenerative brain disorders Archita Khanna, Anamika, and Surendra Kumar Trigun 11. Sirtuins and stem cell maintenance, proliferation, and differentiation Ryan A. Denu and Peiman Hematti 12. Sirtuins in mechanistic target of rapamycin complex 1 signaling J. Burillo, P. Marqués, B. Jiménez, C. González-Blanco, M. Benito, and C. Guillén 13. Free-radical redox timer, sirtuins and aging: from chemistry of free radicals to systems theory of reliability Vitaly K. Koltover and Tatjana A. Skipa 14. Sirtuins, mitochondria, and exercise in health and disease Anibh M. Das and Partha Dabke Section II: Sirtuins, cardiovascular disease and end-organ disease 15. Scope to develop sirtuins modulators as a therapy to attenuate cardiac complications Bugga Paramesha and Sanjay K. Banerjee 16. Role of sirtuins in cardiovascular diseases Venkatraman Ravi, Sneha Mishra, and Nagalingam Ravi Sundaresan 17. Targeting sirtuins to modulate energy metabolism in heart disease Tsunehisa Yamamoto and Ken Shinmura 18. Sirtuin 1 mediates hepatoprotective effects of resveratrol-like compounds in experimental liver injury Hassan Farghali, Mighty Kgalalelo Kemelo, and Nikolina Kutinová Canová 19. Sirtuins as key players in aging and kidney dysfunction Luca Perico and Ariela Benigni 20. Role of sirtuins in liver diseases D. Ezhilarasan and M. Najimi 22. Vitagenes in avian biology: protective functions of sirtuins Peter F. Surai, Ivan I. Kochish, and Vladimir I. Fisinin 23. Sirtuins in hematopoiesis and blood malignancies Berta N. Vazquez, Irene Fernández-Duran, and Alejandro Vaquero Index
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