Skin Tissue Models
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Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury - from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as…mehr

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Produktbeschreibung
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury - from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies.

The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that canreplace animal models.
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Autorenporträt
Alexandra Pinto Marques graduated in Biochemistry (1997) in the Faculty of Sciences of the University of Porto, Portugal, attended a one year specialisation course as part of the Biomedical Engineering Master/Doctoral Programme at the Faculty of Engineering of the University of Porto (1998) and obtained a PhD in Materials Science and Technology - Biomaterials in the University of Minho, Portugal and in cooperation with the University of Liverpool, UK (2004). She is Principal Investigator, a founder member and Vice-Director of the 3B's Research Group, a Research Unit of the University of Minho, Portugal, where she has been build her career in the field of skin tissue engineering. She has been integrating stem cells and biomaterials knowledge into tissue engineering as a way to define innovative strategies to improve the functionality of skin tissue engineered constructs. The establishment of in vitro 3D culture platforms to understand cellular crosstalk as well to be able to modul

ate the engineered constructs outcome has been the focus of her work. She has been awarded successive career grants among which a Consolidator Grant from the European Research Council (2016).

Rogério P. Pirraco (born 1982 Porto, Portugal) concluded his four year-graduation in Applied Biology in 2005, at the University of Minho and his PhD at the same university in 2011. During his PhD, he spent a total of one year at Professor Teruo Okano's Institute of Advanced Biomedical Engineering and Science of the Tokyo's Women Medical University in Tokyo, Japan, where he acquired knowledge in cell sheet engineering and its application in animal models. In 2016, Rogério got a 5 year FCT IF contract (career development grant from the Portuguese Science and Technology Agency) that will allow him to pursue his research interests in an independent way. Currently, his research interests are focused on the use of cell sheet engineering, stem cells and hypoxia for Tissue Engineering strategies.