Iron deficiency is the most prevalent micronutrient deficiency in the world today. It affects millions of individuals throughout their lifecycle, particularly infants and the pregnant women, but also older children, adolescents and women of reproductive age. In developing countries, the prevalence of iron deficiency is high and is due mainly to a low intake of bioavailable iron and may also co-exists with malnutrition, vitamin A deficiency, foliate deficiency and infection. Sleep deprivation disrupts vital biological processes that are necessary for cognitive ability and physical health, but the effect on haematological indices of anaemic individual are largely unknown. The purpose of this present study is to determine the effect of sleep deprivation on red blood cell morphology in rats induced with iron deficiency anaemia. The haematological parameter of anaemic rats fed with garri was investigated. Garri, popular Nigerian fermented cassava gruel was used to feed rats for twenty-five days and were later sleep deprived for 7days. Thirty rats were divided into Groups I, II, III and IV respectively. Result suggested that nutrients rich in iron content should be adopted in daily diet