Small Molecules in Neurodegeneration

Herausgeber: Dar, Nawab John; Bhat, Shahnawaz Ali

• Gebundenes Buch

Produktbeschreibung

Neurodegenerative diseases cast a long shadow over millions of lives, stealing memories, independence, and futures. This book investigates deep into the intricacies of small molecules, exploring their potential to unravel the mysteries of neurodegenerative diseases and pave the way for innovative therapeutic interventions.

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Produktdetails

• Verlag: Taylor & Francis Ltd
• Seitenzahl: 274
• Erscheinungstermin: 13. März 2025
• Englisch
• Abmessung: 254mm x 178mm
• ISBN-13: 9781032857282
• ISBN-10: 1032857285
• Artikelnr.: 71808136

Autorenporträt

Dr. Nawab John Dar is at the Salk Institute for Biological Studies in La Jolla, California, where he is part of a research group led by Professor Pamela Maher. His research journey began after graduating from the CSIR-Indian Institute of Integrative Medicine in India, and he has since been dedicated to advancing the understanding of neurodegenerative disorders, particularly Alzheimer's disease. Dr. Dar's work focuses on exploring the neuroprotective potential of bioactive compounds and investigating the role of oxytosis/ferroptosis in Alzheimer's disease. His goal is to identify targets for effective therapies against Alzheimer's. Beyond his scientific endeavors, Dr. Dar is a committed educator and advocate for raising awareness about neurodegenerative diseases, emphasizing the importance of small molecules in targeting various aspects of neurodegeneration. His work not only sheds light on the potential of these molecules but also offers hope for effective treatments for millions affected by these conditions. Dr. Shahnawaz Ali Bhat is an Assistant Professor in the Department of Zoology at Aligarh Muslim University (AMU), Aligarh, India. Currently his research program focuses on deciphering the molecular and cellular processes/pathways involved in the pathogenesis of neurodegenerative diseases and metabolic disorders. Further, he is also interested in neuropharmacological and neurotoxicological studies to screen or identify various bioactive molecules for effective prevention of neurodegenerative diseases and hypertension-induced neurodegeneration.

Inhaltsangabe

Chapter 1. Introduction to Neurodegenerative Diseases. Chapter 2. Small
molecules: An emerging therapeutic frontier. Chapter 3. Small molecules in
multiple sclerosis: An update. Chapter 4. Andrographolide in Neurological
Disorders: a detailed overview. Chapter 5. Natural Products as
Neuroprotective Agents. Chapter 6. Medicinal Chemistry and the Design of
Small Molecules. Chapter 7. Neurotrophic Factors and Small Molecule
Mimetics. Chapter 8. Repurposed Drugs: Expanding the Therapeutic Resource.
Chapter 9. Integrating Small Molecules into Multimodal Treatment
Strategies. Chapter 10. Advances in Small Molecule Delivery Systems for the
Treatment of Neurodegenerative Disease. Chapter 11. An Enigmatic role of
Small Molecule Therapeutics in Neurodegeneration. Chapter 12. Bridging the
Gap in Neurodegenerative Disease Therapy (NDT). Chapter 13. Ethical and
Economic Considerations in Small Molecule Therapy.