Smoking is a major public health problem worldwide. Smoking cessation poses many difficulties, with relapse the main risk.The aims of our study were to assess the motivation to stop smoking among smokers with a hospitalized loved one, and to study the particularities of their smoking and associated mood disorders.We carried out a prospective, cross-sectional study over a 2-month period on 70 smokers with a close relative hospitalized in the respiratory department. A questionnaire was administered to assess anxiety-depressive disorders (Hospital Anxiety and Depression Scale), dependence (Fagerström score) and motivation to stop smoking (Q-MAT scale). A telephone call was made at 3 months to reassess the smoking profile.